Drugs A - Z
Buprenorphine Hydrochloride Solution for injection
Generic Name: buprenorphine injection
Brand Names: Buprenex
What is this medicine?BUPRENORPHINE (byoo pre NOR feen) is a pain reliever. It is used to treat moderate to severe pain.
What should I tell my health care provider before I take this medicine?They need to know if you have any of these conditions:
- brain tumor
- drink more than 3 alcohol-containing drinks per day
- drug abuse or addiction
- head injury
- lung disease such as asthma or COPD
- an unusual or allergic reaction to buprenorphine, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
How should I use this medicine?This medicine is for injection into a vein. It is usually given by a health care professional in a hospital or clinic setting.
If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.
It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?Do not take this medicine with any of the following medications:
This medicine may also interact with the following medications:
- antibiotics like erythromycin and clarithromycin
- antihistamines for allergy, cough and cold
- barbiturates like phenobarbital
- general anesthetics
- MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
- medicines for depression, anxiety, or psychotic disturbances
- medicines for fungal infections like ketoconazole and itraconazole
- medicines for sleep
- medicines used to treat HIV infection or AIDS like ritonavir, saquinavir, and indinavir
- muscle relaxants
- narcotic medicines (opiates) for pain
- phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
- rifampin or rifampicin
What should I watch for while using this medicine?Tell your doctor or health care professional if your pain does not go away, if it gets worse, or if you have new or a different type of pain. You may develop tolerance to the medicine. Tolerance means that you will need a higher dose of the medicine for pain relief. Tolerance is normal and is expected if you take this medicine for a long time.
Do not suddenly stop taking your medicine because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a non-medical reason. If you have pain, you have a medical reason to take pain medicine. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
There are different types of narcotic medicines (opiates) for pain. If you take more than one type at the same time, you may have more side effects. Give your health care provider a list of all medicines you use. Your doctor will tell you how much medicine to take. Do not take more medicine than directed. Call emergency for help if you have problems breathing.
This medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.
Your mouth may get dry. Drinking water, chewing sugarless gum, or sucking on hard candy may help.
What side effects may I notice from receiving this medicine?Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- anxiety, irritability, nervousness or restlessness
- breathing problems
- cold, clammy skin or sweating
- feeling faint or lightheaded, falls
- stomach pain or vomiting
- swelling of ankles
- trouble passing urine or change in the amount of urine
- yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
- difficulty sleeping
Where should I keep my medicine?Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.
If you are using this medicine at home, you will be instructed on how to store this medicine. Throw away any unused medicine after the expiration date on the label. Discard unused medicine and used packaging carefully. Pets and children can be harmed if they find used or lost packages.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.