Drugs A - Z

Bedaquiline Oral tablet

BEDAQUILINE is used to treat tuberculosis (TB) infections of the lungs.

Generic Name:

What is this medicine?

BEDAQUILINE is used to treat tuberculosis (TB) infections of the lungs.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • heart disease
  • history of irregular heartbeat
  • history of low levels of calcium, magnesium, or potassium in the blood
  • HIV or AIDS
  • if you often drink alcohol
  • liver disease
  • an unusual or allergic reaction to bedaquiline, other medicines, foods, dyes or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Take this medicine with food. Do not cut, crush or chew this medicine. It will be given to you by a health care professional. Take your medicine at regular intervals. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think you are better. Do not skip doses or stop your medicine early.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

It is important not to miss your dose. If you miss a dose during the first 2 weeks, do not make up the missed dose. If you miss a dose after the first 2 weeks, take the missed dose as soon as you can.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • alcohol
  • certain medicines used to treat infections like rifampin, rifapentine, rifabutin

This medicine may also interact with the following medications:

  • antiviral medicines for HIV or AIDS
  • arsenic trioxide
  • certain antipsychotics like haloperidol, pimozide, sertindole, thioridazine, ziprasidone
  • certain medicines used to treat infections like azithromycin, chloroquine, ciprofloxacin, clarithromycin, clofazimine, erythromycin, gemifloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin, pentamidine
  • certain medicines for irregular heart beat like amiodarone, disopyramide, dofetilide, ibutilide, procainamide, propafenone, quinidine, sotalol
  • certain medicines used for nausea like chlorpromazine, droperidol
  • ketoconazole
  • methadone

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Visit your doctor or health care professional for regular check ups. You may need blood work done while you are taking this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • dark urine
  • fast, irregular heartbeat
  • feeling faint or lightheaded, falls
  • general ill feeling or flu-like symptoms
  • light-colored stools
  • loss of appetite, nausea
  • right upper belly pain
  • unusually weak or tired
  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):

  • chest pain or chest tightness
  • headache
  • joint pain
  • rash

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep this medicine in the original container. Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: January 07, 2013
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