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Asenapine Sublingual tablet

It is used to treat schizophrenia and bipolar disorder.

Generic Name: asenapine  |  Brand Name: Saphris

Brand Names: Saphris

What is this medicine?

ASENAPINE (a SEN a peen) is used to treat schizophrenia and bipolar disorder.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • dementia
  • diabetes or a family history of diabetes
  • heart disease
  • history of breast cancer
  • irregular heartbeat or low blood pressure
  • liver disease
  • low blood counts, like low white cell, platelet, or red cell counts
  • Parkinson's disease
  • seizures
  • suicidal thoughts, plans, or attempt by you or a family member
  • an unusual or allergic reaction to asenapine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Follow the directions on the prescription label. Leave the tablet in the package until you are ready to take it. Do not push the tablet through the tablet pack. Peel back the colored tab with dry hands, gently remove the tablet, and place the tablet under your tongue. The tablet will dissolve quickly and be swallowed in your saliva. Do not chew, crush, or swallow the tablet. Do not eat or drink for 10 minutes after taking a dose. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • certain antibiotics like gatifloxacin or moxifloxacin
  • chlorpromazine
  • medicines for irregular heartbeat like amiodarone, disopyramide, dofetilide, ibutilide, procainamide, quinidine, and sotalol
  • thioridazine
  • ziprasidone

This medicine may also interact with the following medications:

  • alcohol
  • carbamazepine
  • cimetidine
  • fluvoxamine
  • imipramine or other tricyclic antidepressants
  • levodopa and other medications for Parkinson's disease
  • medicines for blood pressure
  • medicines for sleep or anxiety
  • other medicines for schizophrenia
  • paroxetine


Last Updated: May 07, 2013
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