• Basic Info
• Clinical Info

What is this medicine?

AMPHOTERICIN (am foe TER i sin) B LIPID COMPLEX is an antifungal medicine. It is used to treat certain kinds of fungal or yeast infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• immune system problems
• other chronic illness
• an unusual or allergic reaction to amphotericin B, other medicines, foods, dyes or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

This medicine is for infusion into a vein. It is usually given by a health care professional in a hospital or clinic setting.

If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

• cidofovir

This medicine may also interact with the following medications:

• certain antibiotics given by injection
• corticotropin
• cyclosporine
• digoxin
• entecavir
• flucytosine
• medicines for fungal infections
• medicines to treat cancer
• muscle relaxers
• pentamidine
• steroid medicines like prednisone or cortisone
• zidovudine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine. Tell your doctor or health care professional if your symptoms do not improve or if you get new symptoms.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash or itching, hives, swelling of the lips, mouth, tongue, or throat
• anxiety, confusion
• breathing trouble
• burning, numbness, tingling
• change in amount or color of urine
• change in hearing, vision
• chest tightness
• fever, chills, infection
• irregular heart beat, blood pressure
• seizure
• unusual bleeding, bruising
• unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• body aches, pain
• cough
• diarrhea
• headache
• flushing, redness of skin
• nausea, vomiting
• pain where injected
• stomach pain
• trouble sleeping

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Last Updated: June 02, 2009