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Amlodipine Besylate, Atorvastatin Calcium Oral tablet

Amlodipine is a calcium-channel blocker used to lower high blood pressure

Generic Name: amlodipine-atorvastatin  |  Brand Name: Caduet

Brand Names: Caduet

What is this medicine?

AMLODIPINE; ATORVASTATIN (am LOE di peen; a TORE va sta tin) is a combination of 2 drugs. Amlodipine is a calcium-channel blocker used to lower high blood pressure. It also relieves chest pain caused by angina. Atorvastatin blocks the body's ability to make cholesterol. It can help lower blood cholesterol for patients who are at risk of getting heart disease or a stroke. It is only for patients whose cholesterol level is not controlled by diet.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • an alcohol problem
  • heart problems, including heart failure or aortic stenosis
  • hormone disorder like diabetes or under-active thyroid
  • infection
  • kidney or liver disease
  • low blood pressure
  • other medical condition
  • recent surgery
  • seizures (convulsions)
  • severe injury
  • an unusual or allergic reaction to Amlodipine; Atorvastatin, medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take the tablets with or without food. Do not change the amount of grapefruit juice you drink from day to day while taking this drug, or avoid grapefruit juice altogether. Take your doses at regular intervals. Do not take your medicine more often then directed. Do not suddenly stop taking this medicine. Ask your doctor or health care professional how you can gradually reduce the dose.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • clofibrate
  • fenofibrate
  • gemfibrozil
  • itraconazole
  • other cholesterol medicines known as statins like fluvastatin, pravastatin and simvastatin
  • telithromycin
  • voriconazole
  • red yeast rice

This medicine may also interact with the following medications:

  • cyclosporine
  • digoxin
  • female hormones, like estrogens or progestins and birth control pills
  • grapefruit juice
  • medicines for fungal infections like fluconazole, itraconazole, ketoconazole, voriconazole
  • medicines for high blood pressure
  • niacin
  • some antibiotics like clarithromycin, erythromycin, and troleandomycin

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. You will need to have regular tests to make sure your liver is working properly.

Tell your doctor or health care professional as soon as you can if you get any unexplained muscle pain, tenderness, or weakness, especially if you also have a fever and tiredness. Your doctor or health care professional may tell you to stop taking this medicine if you develop muscle problems. If your muscle problems do not go away after stopping this medicine, contact your health care professional.

This medicine contains a cholesterol lowering agent, but is only part of a total cholesterol-lowering program. Your physician or dietitian can suggest a low-cholesterol and low-fat diet that will reduce your risk of getting heart and blood vessel disease. Avoid alcohol and smoking, and keep a proper exercise schedule.

Check your blood pressure and pulse rate regularly. Ask your doctor or health care professional what your blood pressure and pulse rate should be and when you should contact him or her.

This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.

You may feel dizzy or lightheaded. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Avoid alcoholic drinks. They can make you more dizzy, increase flushing and rapid heartbeats.


Last Updated: November 06, 2012
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