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Amiodarone Hydrochloride Solution for injection

It helps make your heart beat regularly

Generic Name: amiodarone injection  |  Brand Name: Cordarone

Brand Names: Nexterone, Amiodarone Hydrochloride Novaplus, Amiodarone Hydrochloride, Cordarone

There is an FDA Alert for this drug. Click here to view it.

What is this medicine?

AMIODARONE (a MEE oh da rone) is an antiarrhythmic drug. It helps make your heart beat regularly. Because of the side effects caused by this medicine, it is only used when other medicines have not worked.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • liver disease
  • lung disease
  • other heart problems
  • thyroid disease
  • an unusual or allergic reaction to amiodarone, iodine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • abarelix
  • amoxapine
  • apomorphine
  • arsenic trioxide
  • certain macrolide antibiotics
  • certain quinolone antibiotics
  • cisapride
  • droperidol
  • haloperidol
  • hawthorn
  • levomethadyl
  • maprotiline
  • medicines for malaria like chloroquine and halofantrine
  • medicines for mental depression such as tricyclic antidepressants
  • medicines to control heart rhythm like disopyramide, dofetilide, ibutilide, propafenone, sotalol
  • methadone
  • mibefradil
  • pentamidine
  • phenothiazines like chlorpromazine, mesoridazine, and thioridazine
  • pimozide
  • probucol
  • ranolazine
  • red yeast rice
  • sertindole
  • vardenafil
  • ziprasidone

This medicine may also interact with the following medications:

  • beta-blockers or calcium-channel blockers, often used for high blood pressure or heart problems
  • cholestyramine
  • cimetidine
  • clopidogrel
  • cyclosporine
  • dextromethorphan
  • digoxin
  • diuretics
  • fentanyl
  • flecainide
  • fluindione
  • general anesthetics
  • grapefruit juice
  • lidocaine
  • loratadine
  • medicines for fungal infections like ketoconazole, fluconazole, and itraconazole
  • medicines for HIV, AIDS
  • medicines for seizures such as phenytoin
  • medicines for thyroid problems
  • medicines to lower cholesterol such as atorvastatin, cerivastatin, lovastatin, or simvastatin
  • methotrexate
  • procainamide
  • quinidine
  • rifampin, rifabutin, or rifapentine
  • St. John's Wort
  • trazodone
  • warfarin

What should I watch for while using this medicine?

Your condition will be monitored closely when you first begin therapy. This drug is first started in a hospital or other monitored health care setting. Once you are on maintenance therapy, visit your doctor or health care professional for regular checks on your progress. Because your condition and use of this medicine carry some risk, it is a good idea to carry an identification card, necklace or bracelet with details of your condition, medications, and doctor or health care professional.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Your eyes may get dry while you are using this medicine. It may be helpful to use a lubricating eye solution or artificial tears solution. Check with your doctor or health care professional for regular eye examinations.

If you are going to have surgery or a procedure that requires contrast dyes, tell your doctor or health care professional that you are taking this medicine.


Last Updated: July 16, 2010
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