Drugs A - Z

Alvimopan Oral capsule

It is used to help the gut function after having gut surgery.

Generic Name: alvimopan

Brand Names: Entereg

There is an FDA Alert for this drug. Click here to view it.

  • Only for short-term (15 doses) use in hospitalized patients. (See MI under Cautions.)
  • For use only by hospitals enrolled in the Entereg® Access Support and Education (EASE®) program. (See Restricted Distribution Program under Dosage and Administration.)

REMS:

FDA approved a REMS for alvimopan to ensure that the benefits of a drug outweigh the risks. The REMS may apply to one or more preparations of alvimopan and consists of the following: elements to assure safe use, communication plan, and implementation system. See the FDA REMS page ([Web]) or the ASHP REMS Resource Center ([Web]).

What is this medicine?

ALVIMOPAN (AL vi MOE pan) is used to help the gut function after having gut surgery.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • heart disease
  • kidney disease
  • liver disease
  • taking pain medications (e.g., codeine, morphine)
  • undergoing surgery for stomach or intestinal blockage
  • an unusual or allergic reaction to alvimopan, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. It will only be given to you by a health care professional while you are in the hospital.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

It is important not to miss your dose. Talk to your doctor or health care professional if you miss a dose.

What may interact with this medicine?

  • amiodarone
  • bepridil
  • cyclosporine
  • diltiazem
  • itraconazole
  • narcotic medicines for pain
  • quinidine
  • quinine
  • spironolactone
  • verapamil

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing difficulties
  • dizziness
  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • back pain
  • constipation

Where should I keep my medicine?

This does not apply.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: March 17, 2009
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