Alprostadil Solution for injection

What is this medicine?

ALPROSTADIL (al PROS ta dil) is a natural protein. It is used to treat erectile dysfunction (ED). This medicine helps to create and maintain an erection.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• an abnormally formed penis
• have been advised not to engage in sexual activity
• leukemia
• penile implant
• sickle cell disease or trait
• tumor of the bone marrow (multiple myeloma)
• an unusual or allergic reaction to alprostadil or other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

This medicine is for injection into the penis. You will be taught how to use this medicine. Use exactly as directed. Do not take your medicine more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

• medicines for blood pressure

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Contact your doctor or health care professional immediately if the erection lasts longer than 4 hours or if it becomes painful. This may be a sign of priapism and must be treated immediately to prevent permanent damage.

Do not change the dose of your medication. Call your doctor or health care professional to determine if your dose needs to be changed.

This medicine does not protect you or your partner against HIV infection (the virus that causes AIDS) or other sexually transmitted diseases.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• prolonged or painful erection (lasting longer than 4 hours)

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• bleeding, bruising, or pain at site of injection
• change in blood pressure

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of reach of children.

Store at or below 25 degrees C (77 degrees F) for up to 3 months. Do not freeze.

NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.