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Alogliptin, Pioglitazone Oral tablet

This medicine lowers blood sugar

Generic Name:

What is this medicine?

ALOGLIPTIN; PIOGLITAZONE (al oh glip tin ; pye oh GLI ta zone) is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with diet and exercise.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • bladder cancer
  • diabetic ketoacidosis
  • eye disease called macular edema
  • heart disease
  • heart failure
  • kidney disease
  • liver disease
  • pancreatitis
  • polycystic ovary syndrome
  • premenopausal
  • previous swelling of the tongue, face, or lips with difficulty breathing, difficulty swallowing, hoarseness, or tightening of the throat
  • swelling of the arms, legs, or feet
  • type 1 diabetes
  • an unusual or allergic reaction to alogliptin, pioglitazone, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. Do not cut, crush or chew this medicine. Take your dose at the same time each day. Do not take more often than directed. Do not stop taking except on your doctor's advice.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

-gatifloxacin
This medicine may also interact with the following medications:

-alcohol
-atorvastatin
-digoxin
-female hormones, like estrogens or progestins and birth control pills
-fexofenadine
-insulin
-ketoconazole
-midazolam
-nifedipine
-ranitidine
-rifampin
-steroid medicines like prednisone or cortisone
-sulfonylureas like glimepiride, glipizide, glyburide
-thyroid medicines

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Your health care professional will have to check blood tests regularly to assess the effect of this medication on your liver.

Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.

Do not skip meals. Ask your doctor or health care professional if you should avoid alcohol.

If you have symptoms of low blood sugar, eat or drink something containing sugar at once, and contact your doctor or health care professional. Make sure family members know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar like seizures or unconsciousness. They must get medical help at once.

This medicine may increase your risk of having some heart problems. Get medical help right away if you have any chest pain or tightness, or pain that radiates to the jaw or down the arm, and shortness of breath. These may be signs of a serious medical condition.

This medicine may cause ovulation in premenopausal women who do not have regular monthly periods. This may increase your chances of becoming pregnant. Talk with your doctor or health care professional about your birth control options while taking this medicine. Contact your doctor or health care professional right away if think you are pregnant.

Wear a medical ID bracelet or chain, and carry a card that describes your disease and details of your medicine and dosage times.


Last Updated: February 08, 2013
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