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Adapalene Topical gel

It is applied to the skin to treat mild to moderate acne.

Generic Name: adapalene topical  |  Brand Name: Differin

Brand Names: Differin

What is this medicine?

ADAPALENE (a DAP a leen) is applied to the skin to treat mild to moderate acne.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • eczema
  • seborrheic dermatitis
  • skin abrasions
  • sunburn
  • an unusual or allergic reaction to adapalene, vitamin A, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for external use only, do not take by mouth. Follow the directions on the prescription label. Make sure the skin is clean and dry. Apply just enough to cover the affected area. Rub in gently. Do not get in the eyes, inside the nose, on wounds, or any other sensitive areas of skin.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, skip that dose and continue with your regular schedule. Do not use extra doses, or use for a longer period of time than directed by your doctor or health care professional.

What may interact with this medicine?

  • topical antibiotics like clindamycin or erythromycin

What should I watch for while using this medicine?

Your acne may get worse at first, and then should start to get better. It may take 2 to 12 weeks before you see the full effect.

Do not wash your face more than 3 times a day unless your doctor or health care professional tells you to. Do not use products that may dry the skin like medicated cosmetics, products that contain alcohol, or abrasive soaps or cleaners. Do not use other acne or skin treatment on the same area that you use this medicine unless your doctor or health care professional tells you to. If you use these together they can cause severe skin irritation.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • severe burning, reddening, crusting, or swelling of the treated areas

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • inflamed, stinging, and irritated skin
  • skin that peels after a few days of use

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Do not freeze. Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


Last Updated: February 15, 2013
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