Drugs A - Z
Antitussive Combinations with Analgesics Oral capsule, liquid filled
Generic Name: APAP/dextromethorphan/pseudoephedrine | Brand Name: Comtrex
What is this medicine?ACETAMINOPHEN; DEXTROMETHORPHAN; PSEUDOEPHEDRINE (a set a MEE noe fen; dex troe meth OR fan; soo doe e FED rin) is a combination of a pain reliever, a cough suppressant, and a decongestant. It is used to treat the aches and pains, fever, cough and congestion of a cold. This medicine will not treat an infection.
What should I tell my health care provider before I take this medicine?They need to know if you have any of these conditions:
- heart disease
- high blood pressure
- if you frequently drink alcohol containing drinks
- liver disease
- taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
- thyroid disease
- trouble passing urine
- an unusual or allergic reaction to acetaminophen, dextromethorphan, pseudoephedrine, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
How should I use this medicine?Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not cut, crush, or chew this medicine. Take your medicine at regular intervals. Do not take it more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years of age for selected conditions, precautions do apply.
What if I miss a dose?If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?Do not take this medicine with any of the following medications:
- ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
- MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
- stimulant medicines like dextroamphetamine and others
This medicine may also interact with the following medications:
- medicines for blood pressure
- medicines for chest pain like isosorbide dinitrate, nitroglycerin
- medicines for depression, anxiety, or psychotic disturbances
- medicines for sleep during surgery
- other medicines for cold, cough or allergy
- other medicines with acetaminophen
- St. John's Wort
What should I watch for while using this medicine?Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Let your doctor know if you have pain, nasal congestion, or cough that gets worse or lasts for more than 7 days. Call your doctor if you have a fever that gets worse or lasts for more than 3 days. If you have a cough that comes back or occurs with rash or headache see your doctor.
Do not take other medicines that contain acetaminophen with this medicine. Always read labels carefully. If you have questions, ask your doctor or pharmacist.
If you take too much acetaminophen get medical help right away. Too much acetaminophen can be very dangerous and cause liver damage. Even if you do not have symptoms, it is important to get help right away.
What side effects may I notice from receiving this medicine?Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- chest pain, tightness
- dizziness, nervousness, or sleeplessness
- fast, irregular heartbeat
- trouble passing urine or change in the amount of urine
- unusual bleeding or bruising
- unusually weak or tired
- yellowing of skin or eyes
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
- dry eyes, mouth
- loss of appetite
- stomach upset
Where should I keep my medicine?Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture and humidity. Throw away any unused medicine after the expiration date.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.