Second-Look Surgery

Definition

Second-look surgery is performed after a procedure or course of treatment to determine if the patient is free of disease. If disease is found, additional procedures may or may not be performed at the time of second-look surgery.


Purpose

Second-look surgery may be performed under numerous circumstances on patients with various medical conditions.


Cancer

A second-look procedure is sometimes performed to determine if a cancer patient has responded successfully to a particular treatment. Examples of cancers that are assessed during second-look surgery are ovarian cancer and colorectal cancer. In many cases, before a round of chemotherapy and/or radiation therapy is started, a patient will undergo a surgical procedure called cytoreduction to reduce the size of a tumor. This debulking increases the sensitivity of the tumor and decreases the number of necessary treatment cycles. Following cytoreduction and chemotherapy, a second-look procedure may be necessary to determine if the area is cancer-free.

An advantage to second-look surgery following cancer treatment is that if cancer is found, it may be removed during the procedure in some patients. In other cases, if a tumor cannot be entirely removed, the surgeon can debulk the tumor and improve the patient's chances of responding to another cycle of chemotherapy. However, second-look surgery cannot definitively prove that a patient is free of cancer; some microscopic cancer cells can persist and begin to grow in other areas of the body. Even if no cancer is found during second-look surgery, the rate of cancer relapse is approximately 25%.

Pelvic disease

Second-look surgery may benefit patients suffering from a number of different conditions that affect the pelvic organs. Endometriosis is a condition in which the tissue that lines the uterus grows elsewhere in the body, usually in the abdominal cavity, leading to pain and scarring. Endometrial growths may be surgically removed or treated with medications. A second-look procedure may be performed following the initial surgery or course of medication to determine if treatment was successful in reducing the number of growths. Additional growths may be removed at this time.

Second-look surgery may also be performed following the surgical removal of adhesions (bands of scar tissue that form in the abdomen following surgery or injury) or uterine fibroids (noncancerous growths of the uterus). If the results are positive, an additional procedure may be performed to remove the adhesions or growths. Patients undergoing treatment for infertility may benefit from a second-look procedure to determine if the cause of infertility has been cured before ceasing therapy.



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