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What is Remission in Psoriasis?
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Patient Experience With Psoriasis Therapies
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Combination Therapy in the Treatment of Psoriasis
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Living With Psoriasis: Quality of Life On Treatment
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Biologics for Psoriasis: What's A Good Treatment Plan?
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Gaining Experience with Biologics for Psoriasis
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Named for the Greek word psnullra meaning itch, psoriasis is a chronic, non-contagious disease characterized by inflamed lesions covered with silvery-white scabs of dead skin.
Normal skin cells mature and replace dead skin every 28 to 30 days. In psoriasis, the immune system triggers the immune system to make T cells, a type of white blood cell, that cause skin cells to mature in two to three days. Because the body cannot shed old skin as rapidly as the new cells appear, raised patches of dead skin form on the body.
Psoriasis is considered mild if it affects less than 5 percent of the surface of the body; moderate, if 5 to 30 percent of the skin is involved, and severe, if the disease affects more than 30 percent of the body surface.
There is no cure for psoriasis. The disease is managed through treatment. Psoriasis can seriously impact children's lives when the hands and feet are affected so the children cannot take notes or walk or play, or when the disease becomes so widespread that the immune system becomes compromised. Children also experience low self-esteem and depression because of the disfiguring aspects of the disease.
Dermatologists distinguish different forms of psoriasis according to what part of the body is affected, how severe symptoms are, how long they last, and the pattern formed by the scales. Though children usually have only one form of the disease, some do experience two more types of psoriasis throughout their lifetimes.
PLAQUE PSORIASIS Plaque psoriasis (psoriasis vulgaris), the most common form of the disease, is characterized by small, red bumps that enlarge, become inflamed, and form scales. The top scales flake off easily and often, but those beneath the surface of the skin clump together. Removing these scales exposes tender skin, which bleeds and causes the plaques (inflamed patches of skin) to grow.
Plaque psoriasis can develop on any part of the body, but most often occurs on the elbows, knees, scalp, and trunk. Patches of psoriasis are found in the scalp for nearly half of all psoriasis sufferers.
GUTTATE PSORIASIS Named for the Latin word gutta, which means "a drop," guttate psoriasis is characterized by small, red, drop-like dots that enlarge rapidly and may be somewhat scaly. Often found on the arms, legs, trunk, scalp, and sometimes in the diaper area, guttate psoriasis can clear up without treatment or disappear and resurface in the form of plaque psoriasis.
Guttate psoriasis is the most common form of psoriasis in children. It usually first appears in children around four or five years old after a streptococcal infection.
PUSTULAR PSORIASIS Pustular psoriasis usually occurs in adults but can occur in children and adolescents. It is characterized by blister-like lesions filled with non-infectious pus and surrounded by reddened skin. Pustular psoriasis, which can be limited to one part of the body or can be widespread, may be the first symptom of psoriasis or develop in a patient with chronic plaque psoriasis.
Generalized pustular psoriasis is also known as Von Zumbusch pustular psoriasis. Widespread, acutely painful patches of inflamed skin develop suddenly. Pustules appear within a few hours, then dry, and peel within two days. It can make life-threatening demands on the heart and kidneys.
Palomar-plantar pustulosis (PPP) generally appears between the ages of 20 and 60.
INVERSE PSORIASIS Inverse psoriasis occurs in the armpits and groin, under the breasts, and in other areas where skin flexes or folds. This disease is characterized by smooth, inflamed lesions and can be debilitating.
ERYTHRODERMIC PSORIASIS Characterized by severe scaling, itching, and pain that affects most of the body, erythrodermic psoriasis disrupts the body's chemical balance and can cause severe illness or even death when the body's immune system becomes compromised. Erythrodermic psoriasis interferes with the body's ability to control temperature and prevent infections. This particularly inflammatory form of psoriasis can be the first sign of the disease but often develops in patients with a history of plaque psoriasis.
PSORIATIC ARTHRITIS About 10 percent of patients with psoriasis develop a complication called psoriatic arthritis. This type of arthritis can be slow to develop and mild, or it can develop rapidly. Symptoms of psoriatic arthritis include:
Children who have psoriatic arthritis also have nail deformations, usually pitting of the fingernails or toenails. Size, shape, and depth of the marks vary, and affected nails may thicken, yellow, or crumble. The skin around an affected nail is sometimes inflamed, and the nail may peel away from the nail bed.
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Author Info: Janie Franz, Maureen Haggerty, Thomson Gale, Gale, Detroit, Gale Encyclopedia of Children's Health, 2006 |