Probiotic foods and dietary supplements have been recommended as treatments for a variety of diseases and disorders, ranging from problems confined to the digestive tract to general health issues.
Intestinal complaints
To summarize, probiotic organisms, in particular the LGG strain, have been shown to be helpful in managing the following intestinal disorders:
Pseudomembranous colitis, a potentially life-threatening inflammation of the colon caused by an overgrowth of the bacteriumClostridium difficile as a result of the patient's having taken antibiotics that causes profuse watery diarrhea, cramps, and low-grade fever.
bacterial overgrowth in the small bowel by organisms such as Helicobacter pylori, implicated in gastric ulcers (studies have demonstrated benefit but not cure)
Lifestyle-related disorders
Some supporters of probiotics go beyond applications limited to treatment of intestinal disorders. In keeping with the theory of autointoxication, they maintain that probiotics are effective in treating a wide range of chronic and acute illnesses thought to result from a condition called intestinal dysbiosis, or poor intestinal health quality due to toxic buildup, putrefaction, and leaky gut syndrome. Intestinal dysbiosis is defined as an imbalance among the various microorganisms in the digestive tract. This imbalance is attributed to a combination of Western high-protein diets, stress, environmental pollution, and allopathic medications. Putrefaction is believed to result from a low fiber diet, chronic constipation or sluggish colon, and poor food combining leading to increased gut fermentation. Leaky gut syndrome is the term used to suggest that the effect of these toxins on the intestinal cell walls is damaging to intestinal integrity, and as a result, large molecules of relatively undigested food and toxins cross the intestinal membrane into the blood stream.
Some alternative practitioners maintain that the following diseases and disorders are directly related to intestinal dysbiosis or may also be beneficially treated with probiotics:
high blood pressure (research has demonstrated a systolic blood pressure decrease of 10–20 mm Hg with the use of a fermented milk product
high cholesterol, (clinical studies have not been conclusive; as one source said, "Evidence is not over-whelming")
cancer (by decreasing exposure from gene-altering substances)
menopausal problems in women (by improving the liver's ability to detoxify and eliminate hormonal metabolites)
vaginosis (once thought to be relatively benign, now implicated in easier transmission of sexual diseases, pelvic inflammatory disease, and pregnancy-related complications, improved by reducing vaginal pH which inhibits growth of unfavorable bacteria)
allergies and asthma (a double-blind placebo-controlled study demonstrated a 50% drop in children followed up to two years of age)
kidney stones, by inhibiting the absorption of oxalate from the intestines
More specifically, probiotic foods and dietary supplements are claimed to counteract intestinal dysbiosis in the following ways:
production of vitamins. Friendly bacteria are said to manufacture vitamin B3, vitamin B6, and folic acid.
anti-tumor and anti-cancer activity
suppression of pathogenic microorganisms in favor of the non-pathogenic
relief of anxiety symptoms through indirect detoxification
protection against radiation and other environmental toxins
support of the immune system, by reducing immune load
recirculation of female hormones in the bloodstream by a cleaner liver and cleaner blood, thus maintaining higher levels of estrogen in menopausal women