Prior to the discovery of penicillin and other antibiotics, bacterial pneumonia was almost always fatal. In the early 2000s, especially given early in the course of the disease, antibiotics are very effective against bacterial causes of pneumonia. Penicillin was, as of 2004, still the first choice for treating children with pneumonia unless the child is known to be penicillin-resistant. Oral
Linezolid (Zyvox), the first of a new line of antibiotics known as oxazolidinones, is used to treat penicillin-resistant organisms that cause pneumonia. Another newer drug known as ertapenem (Invanz) is reported to be effective in treating bacterial pneumonia.
The child is also be given fluids and possibly drug therapy to thin mucus secretions (mucolytic agents) or medication to open the airways of the lung (brochodilators). Cough suppressants may be given as well as pain medication and fever-reducing medication. Hospitalized children may receive extra oxygen, respiratory therapy, and intravenous antibiotics and fluids.
Vitamin C is known to improve immune response and to help reduce inflammation. Grape seed extract enhances immune system functioning and helps protect lung tissue. These are adjunctive measures that do not destroy the causative organism as antibiotics do. Although garlic and certain herbs such as yerba mansa may have antibiotic properties, they cannot replace specific antibiotics used to treat pneumonia.
Prognosis varies according to the type of organism causing the infection, the status of the immune system, and the overall health of the affected child. Generally, there are lower mortality rates from pneumonia in the United States than elsewhere in the world. Streptococcus pneumoniae, the most common organism causing pneumonia, has a significantly lower death rate of about 5 percent. More complications occur in the very young or very old with multiple areas of the lung infected simultaneously. The presence of chronic illnesses such as diabetes, cirrhosis, and congestive heart failure may increase the chance of complications. Individuals with immunodeficiency disorders, various types of cancer, or AIDS are also more prone to complications. In children, cystic fibrosis, aspiration problems, immunodeficiencies, and congenital or acquired lung malformation may increase the risk of pneumonia from S. pneumoniae.
Alveoli—The tiny air sacs clustered at the ends of the bronchioles in the lungs in which oxygen-carbon dioxide exchange takes place.
Aspiration—The process of removing fluids or gases from the body by suction. Also refers to the inhalation of food or liquids into the lungs.
Cilia—Tiny hairlike projections on certain cells within the body. Cilia produce lashing or whipping movements to direct or cause motion of substances or fluids within the body. Within the respiratory tract, the cilia act to move mucus along, in an effort to continually flush out and clean the respiratory tract.
Consolidation—A condition in which lung tissue becomes firm and solid rather than elastic and air-filled, arising because of accumulated fluids and tissue debris.
Culture—A test in which a sample of body fluid is placed on materials specially formulated to grow microorganisms. A culture is used to learn what type of bacterium is causing infection.
Cyanosis—A bluish tinge to the skin that can occur when the blood oxygen level drops too low.
Pneumocystis carinii—An organism that causes pneumonia in immunodeficient individuals, such as people with AIDS.
Respiratory system—The organs that are involved in breathing: the nose, the throat, the larynx, the trachea, the bronchi and the lungs. Also called the respiratory tract.
Sputum—The substance that is coughed up from the lungs and spit out through the mouth. It is usually a mixture of saliva and mucus, but may contain blood or pus in patients with lung abscess or other diseases of the lungs.
Stroma—A term used to describe the supportive tissue surrounding a particular structure. An example is the tissue that surrounds and supports the actually functional lung tissue.
Tachypnea—Rapid breathing.
Recovery following pneumonia with Mycoplasma pneumoniae is nearly 100 percent. However, in the very young or very old or immunodeficient, Staphylococcus aureus has a death rate of 30 to 40 percent. Similarly,
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Author Info: L. Lee Culvert, Rosalyn Carson-DeWitt MD, Rebecca J. Frey PhD, Thomson Gale, Gale, Detroit, Gale Encyclopedia of Children's Health, 2006 |