Orthostatic hypotension is an abnormal decrease in blood pressure when a person stands up. This may lead to fainting.
When a person stands upright, a certain amount of blood normally pools in the veins of the ankles and legs. This pooling means that there is slightly less blood for the heart to pump and causes a drop in blood pressure. Usually, the body responds to this drop so quickly, a person is unaware of the change. The brain tells the blood vessels to constrict so they have less capacity to carry blood, and at the same time tells the heart to beat faster and harder. These responses last for a very brief time. If the body's response to a change in vertical position is slow or absent, the result is orthostatic hypotension. It is not a true disease, but the inability to regulate blood pressure quickly.
Orthostatic hypotension has many possible causes. The most common cause is medications used to treat other conditions. Diuretics reduce the amount of fluid in the body which reduces the volume of blood. Medicines used to expand the blood vessels increase the vessel's ability to carry blood and so lower blood pressure.
If there is a severe loss of body fluid from vomiting, diarrhea, untreated diabetes, or even excessive sweating, blood volume will be reduced enough to lower blood pressure. Severe bleeding can also result in orthostatic hypotension.
Any disease or spinal cord injury that damages the nerves which control blood vessel diameter can cause orthostatic hypotension.
Symptoms of orthostatic hypotension include faintness, dizziness, confusion, or blurry vision, when standing up quickly. An excessive loss of blood pressure can cause a person to pass out.
When a person experiences any of the symptoms above, a physician can confirm orthostatic hypotension if the person's blood pressure falls significantly on standing up and returns to normal when lying down. The physician will then look for the cause of the condition.
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Author Info: Dorothy Elinor Stonely, The Gale Group Inc., Gale, Detroit, Gale Encyclopedia of Medicine, 2002 |