Omega-3 Fatty Acids Health Article

Diabetes

Early studies in laboratories indicate that omega-3 fatty acids in fish oils might prolong life in people with automimmune disorders like diabetes. A new study looked at substituting fish oil for corn oil in diets and found a tendency to suppress immune system dysfunction and prolong life. More studies are required to prove the diet's benefits in humans.

Inflammatory bowel disease

High-dose fish-oil supplements have shown to decrease abdominal cramping, diarrhea, and pain associated with Crohn's disease. In one study of 96 patients, patients who received 4.5 g of omega-3 fatty acids (15 fish oil capsules) required significantly less steroids to control symptoms. In another study of 78 Crohn's disease patients, 59% of patients who received nine fish oil capsules (2.7g of omega-3 fatty acids) daily did not have any disease flare-ups for at least one year compared to 26% recurrence rate in patients who were not given fish oil. Omega-3 fatty acids also are effective in preventing reappearance of Crohn's disease after surgery to remove sections of diseased bowel. In a clinical trial involving 50 patients, patients who received 2.7 grams of omega-3 fats as fish oil cut their rate of disease reappearance in half compared to patients receiving placebo. However, the effectiveness of omega-3 oils varies depending on the type of omega-3 oils being used, length of use, and the patient's diet.

Asthma

Taking high dose omega-3 fatty acids can reduce inflammation of the airways and reduce asthma attacks. According to Donald Rudin, the author of the book titled Omega-3 Oils, allergic disorders such as asthma may be triggered by too much omega-6 and too little omega-3 fats in our body. Excessive amounts of omega-6 prostaglandins cause the body to produce antibodies that cause allergic reactions. Flaxseed or fish oil supplements can keep the omega-6 fats in check and decrease the inflammatory reactions associated with asthma.

Berger's disease (Immunoglobulin A nephropathy)

Omega-3 fats may be effective in treating this autoimmune disease in which kidney function fails over time with few treatment options available. In a large, randomized study of 150 patients, those who received 3 g of omega-3 fatty acids daily for two years had significantly less reduction in renal function than those treated with placebo. Therefore, omega-3 fatty acids appear to have protective effects and may stabilize renal function in these patients.

Raynaud's disease

There have been few studies evaluating the effects of omega-3 fatty acids in treating Raynaud's disease; however, it appears that fish oil supplements may alleviate some blood clotting disorders.

Mental disorders

According to some studies, many common mental disorders, such as depression, bipolar disorder (manic-depression), attention-deficit hyperactive disorder (ADHD), anxiety, or schizophrenia, may be triggered by deficiencies of omega-3 fatty acids and/or B vitamins. The rates of depression are low in countries that eat a lot of fish, while the rate of depression steadily rises in the United States as Americans eat increasingly more processed food and less fresh fish and vegetables containing omega-3 fats. In one study, 53% of bipolar patients on placebo (olive oil) became ill again within four months, while none of the patients who were given 9.6 g daily of omega-3 fatty acids (as fish oil) did. Supplements containing omega-3 fats also reportedly have been effective in children with ADHD precipitated by essential fatty acid deficiencies. Furthermore, a 25% decrease in schizophrenic symptoms was observed in patients receiving eicosapentanoic acid (EPA), one of the omega-3 fatty acids contained in fish oil.

A report in 2001 revealed that omega-3 fatty acids may have effects on stabilizing mood and relieving depression. As studies continue, researchers are finding it more and more evident that omega-3 fatty acids can be effective for treating depression, though they still are un-certain exactly how they work. A 2003 report linked depression to increased risk of sudden cardiac death.

Acquired Immunodeficiency syndrome (AIDS)

In a small study of 20 AIDS patients, those who received fish oil supplement at dosage of 10 g of omega-3 fatty acids per day for 30 days gained more weight (2.4 kg) and significantly lowered their concentrations of tumor necrosis factor, which is believed to cause wasting in AIDS patients, compared to those who did not.

Cancer prevention

Omega-3 fatty acids inhibit tumor growth when injected into animals. Flaxseed oil, which is a plant source of omega-3 fatty acids, has been shown to prevent cancer of the breast, colon and prostate. The Mediterranean diet, which is heart healthy, also can decrease risk of getting cancer. Omega-3 fats, it seems, strengthen the immune systems and inhibit the inflammation and blood circulation of the tumors.