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What are the Various Diagnostic Imaging Tests?
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MRI scanning should not be used when there is the potential for an interaction between the strong MRI magnet and metal objects that might be imbedded in a patient's body. The force of magnetic attraction on certain types of metal objects (including surgical steel) could move them within the body and cause serious injury. Metal may be imbedded in a person's body for several reasons.
People with implanted cardiac pacemakers, metal aneurysm clips, or who have broken bones repaired with metal pins, screws, rods, or plates must tell their radiologist prior to having an MRI scan. In some cases (like a metal rod in a reconstructed leg), the difficulty may be overcome.
Patients must tell their doctor if they have bullet fragments or other metal pieces in their body from old wounds. The suspected presence of metal, whether from an old or recent wound, should be confirmed before scanning.
People with significant work exposure to metal particles (e.g., working with a metal grinder) should discuss this with their doctor and radiologist. The patient may need prescan testing—usually a single, regular x ray of the eyes to see if any metal is present.
Chemical agents designed to improve the picture or allow for the imaging of blood or other fluid flow during MRA may be injected. In rare cases, patients may be allergic to, or intolerant of, these agents, and these patients should not receive them. If these chemical agents are to be used, patients should discuss any concerns they have with their doctor and radiologist.
The potential side effects of magnetic and electric fields on human health remain a source of debate. In particular, the possible effects on an unborn baby are not well known. Any woman who is, or may be, pregnant, should carefully discuss this issue with her doctor and radiologist before undergoing a scan.
As with all medical imaging techniques, obesity greatly interferes with the quality of MRI.
In essence, MRI produces a map of hydrogen distribution in the body. Hydrogen is the simplest element known, the most abundant in biological tissue, and one that can be magnetized. It will align itself within a strong magnetic field, like the needle of a compass. The earth's magnetic field is not strong enough to keep a person's hydrogen atoms pointing in the same direction, but the
Once a patient's hydrogen atoms have been aligned in the magnet, pulses of very specific radio wave frequencies are used to knock them back out of alignment. The hydrogen atoms alternately absorb and emit radio wave energy, vibrating back and forth between their resting (magnetized) state and their agitated (radio pulse) state. This comprises the resonance part of MRI.
The MRI equipment records the duration, strength, and source location of the signals emitted by the atoms as they relax and translates the data into an image on a television monitor. The state of hydrogen in diseased tissue differs from healthy tissue of the same type, making MRI particularly good at identifying tumors and other lesions. In some cases, chemical agents such as gadolinium can be injected to improve the contrast between healthy and diseased tissue.
A single MRI exposure produces a two-dimensional image of a slice through the entire target area. A series of these image slices closely spaced (usually less than half an inch) makes a virtual three-dimensional view of the area.
Magnetic resonance spectroscopy (MRS) is different from MRI because MRS uses a continuous band of radio wave frequencies to excite hydrogen atoms in a variety of chemical compounds other than water. These compounds absorb and emit radio energy at characteristic frequencies, or spectra, which can be used to identify them. Generally, a color image is created by assigning a color to each distinctive spectral emission. This comprises the spectroscopy part of MRS. MRS is still experimental and is available only in a few research centers.
Doctors primarily use MRS to study the brain and disorders like epilepsy, Alzheimer's disease, brain tumors, and the effects of drugs on brain growth and metabolism. The technique is also useful in evaluating metabolic disorders of the muscles and nervous system.
Magnetic resonance angiography (MRA) is another variation on standard MRI. MRA, like other types of angiography, looks specifically at fluid flow within the blood (vascular) system, but does so without the injection of dyes or radioactive tracers. Standard MRI cannot make a good picture of flowing blood, but MRA uses specific radio pulse sequences to capture usable signals. The technique is generally used in combination with
MRI technology is also being applied in the evaluation of the pancreatic and biliary ducts in a new study called magnetic resonance cholangiopancreatography (MRCP). MRCP produces images similar to that of endoscopic retrograde cholangiopancreatography (ERCP), but in a non-invasive manner. Because MRCP is new and still very expensive, it is not readily available in most hospitals and imaging centers.
Regardless of the exact type of MRI planned, or area of the body targeted, the procedure involved is basically the same. In a special MRI suite, the patient lies down on a narrow table and is made as comfortable as possible. Transmitters are positioned on the body and the table moves into a long tube that houses the magnet. The tube is as long as an average adult lying down, and is open at both ends. Once the area to be examined has been properly positioned, a radio pulse is applied. Then a two-dimensional image corresponding to one slice through the area is made. The table then moves a fraction of an inch and the next image is made. Each image exposure takes several seconds and the entire exam will last anywhere from 30 to 90 minutes. During this time, the patient must remain still as movement can distort the pictures produced.
Depending on the area to be imaged, the radio-wave transmitters will be positioned in different locations.
Additional probes will monitor vital signs (like pulse, respiration, etc.) throughout the test.
The procedure is somewhat noisy and can feel confining to many patients. As the patient moves through the tube, the patient hears a thumping sound. Sometimes, music is supplied via earphones to drown out the noise. Some patients may become anxious or feel claustrophobic while in the small, enclosed tube. Patients may be reassured to know that throughout the study, they can communicate with medical personnel through an intercom-like system.
Recently, open MRIs have become available. Instead of a tube open only at the ends, an open MRI also has opening at the sides. Open MRIs are preferable for patients who have a fear of closed spaces and become anxious in traditional MRI machines. Open MRIs can also better accommodate obese patients, and allow parents to accompany their children during testing.
If the chest or abdomen is to be imaged, the patient will be asked to hold his to her breath as each exposure is made. Other instructions may be given to the patient as needed. In many cases, the entire examination will be performed by an MRI operator who is not a doctor. However, the supervising radiologist should be available to consult as necessary during the exam, and will view and interpret the results sometime later.
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Author Info: Kurt Richard Sternlof, The Gale Group Inc., Gale, Detroit, Gale Encyclopedia of Cancer, 2002 |