Hand-Foot-Mouth Disease
Definition
Hand-foot-mouth disease is an infection of young children in which characteristic fluid-filled blisters appear on the hands, feet, and inside the mouth.
Description
Coxsackie viruses belong to a family of viruses called enteroviruses. These viruses live in the gastrointestinal tract and are, therefore, present in feces. They can be spread easily from one person to another when poor hygiene allows the virus within the feces to be passed from person to person. After exposure to the virus, development of symptoms takes only four to six days. Hand-foot-mouth disease can occur year-round, although the largest number of cases are in summer and fall months.
An outbreak of hand-foot-mouth disease occurred in Singapore in 2000, with more than 1,000 diagnosed cases, all in children, resulting in four deaths. A smaller outbreak occurred in Malaysia in 2000. In 1998, a serious outbreak of enterovirus in Taiwan resulted in more than 1 million cases of hand-foot-and-mouth disease. Of these, there were 405 severe cases and 78 deaths, 71 of which were children younger than five years of age.
Hand-foot-mouth should not be confused with foot and mouth disease, which infects cattle but is extremely rare in humans. An outbreak of foot and mouth disease swept through Great Britain and into other parts of Europe and South America in 2001.
Demographics
Hand-foot-mouth disease is very common among young children and often occurs in clusters of children who are in daycare together.
Causes and symptoms
Hand-foot-mouth disease is spread when poor hand washing after a diaper change or contact with saliva allows the virus to be passed from one child to another.
Within about four to six days of acquiring the virus, an infected child may develop a relatively low-grade fever, ranging from 99 to 102°F (37.2–38.9°C). Other symptoms include fatigue, loss of energy, decreased appetite, and a sore sensation in the mouth that may interfere with feeding. After one to two days, fluid-filled bumps (vesicles) appear on the inside of the mouth, along the surface of the tongue, on the roof of the mouth, and on the insides of the cheeks. These are tiny blisters, about 3–7 mm in diameter. Eventually, they may appear on the palms of the hands and on the soles of the feet. Occasionally, these vesicles may occur in the diaper region.
The vesicles in the mouth cause the majority of discomfort, and the child may refuse to eat or drink due to pain. This phase usually lasts for an average of a week. As long as the bumps have clear fluid within them, the disease is at its most contagious. The fluid within the vesicles contains large quantities of the causative viruses. Extra care should be taken to avoid contact with this fluid.
