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Diazepam Health Article

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Definition

Diazepam is an antianxiety medication that is also useful in the treatment of muscle spasms and some types of seizures. The drug belongs to the class of medications known as benzodiazepines that depress activity of the central nervous system.

Purpose

Diazepam, which is marketed under the brand names of Valium, Diastat, T-Quil, and Valrelease, is taken by millions of people to relieve feelings of anxiety. As well, the drug can lessen muscle spasms and can control some types of seizures. Diazepam is also used to therapeutically lessen the agitation caused during alcohol withdrawal by someone who is physically addicted to alcohol. Additionally, diazepam is used in the treatment of irritable bowel syndrome and to lessen the symptoms of panic attacks.

Description

Diazepam is supplied as a tablet, as a capsule that releases the active drug at a slower rate, or as a liquid. All three of these forms of the drug are taken orally. The time-release capsule should be swallowed whole. Diazepam should be stored at room temperature in a tightly closed container to avoid alteration in the compound due to excessive heat or moisture. Valium is also available in an injectable form.

Recommended dosage

Diazepam dosage is determined by a physician taking into account the nature of the problem, severity of the symptoms, and the person's response to the drug. Typical adult doses range from 2–10 mg taken two to four times a day. Children and elderly adults will typically receive 1–2 mg one to four times daily.

The dosage of diazepam typically prescribed by a physician is taken anywhere from one to four times each day, depending on the strength of the individual dose. This maintains the concentration of the drug at a therapeutic level, as diazepam is quickly absorbed from the gastrointestinal tract. Peak levels of the drug are reached within a couple of hours after administration, with levels dropping below therapeutic effectiveness within six to eight hours.

Diazepam can be taken with or without food. The liquid form can be mixed with other fluids or select foods such as applesauce.

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Author Info: Brian Douglas Hoyle PhD, The Gale Group Inc., Gale, Detroit, Gale Encyclopedia of Neurological Disorders, 2005
 
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