Blot, Western

BLOT, WESTERN

The blot test is a method used to detect and identify DNA or RNA samples, using absorbent paper electrophoresis. The original test in this group was developed by British biologist M. E. Southern in 1975, and is named the Southern blot test. As related tests using the same general method were developed, they were named for the points of the compass. The Western blot test is a specific test that uses paper electrophoresis to detect HIV (human immunodeficiency virus), and it is widely used in screening for HIV infection.

JOHN M. LAST

(SEE ALSO: HIV/AIDS; Laboratory Services; Screening)