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AIDS Health Article

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Definition

Acquired immune deficiency syndrome (AIDS) is an infectious disease caused by the human immunodeficiency virus (HIV). It was first recognized in the United States in 1981. AIDS is the advanced form of infection with the HIV virus, which may not cause recognizable disease for a long period after the initial exposure (latency). No vaccine is currently available to prevent HIV infection. At present, all forms of AIDS therapy are focused on improving the quality and length of life for AIDS patients by slowing or halting the replication of the virus and treating or preventing infections and cancers that take advantage of a person's weakened immune system.

Description

AIDS is considered one of the most devastating public health problems in recent history. In June 2000, the Centers

Risk of acquiring HIV infection by entry site
Entry site Risk virus reaches entry site Risk virus enters Risk inoculated
Conjuntiva Moderate Moderate Very low
Oral mucosa Moderate Moderate Low
Nasal mucosa Low Low Very low
Lower respiratory Very low Very low Very low
Anus Very high Very high Very high
Skin, intact Very low Very low Very low
Skin, broken Low High High
Sexual:
Vagina Low High High
Penis Low Low High
Ulcers (STD) Medium Low Very high
Blood:
Products High High Low
Shared needles High High High
Accidental needle High Very High Low
Traumatic wound Modest High High
Perinatal High High High

for Disease Control and Prevention (CDC) reported that 120,223 (includes only those cases in areas that have confidential HIV reporting) in the United States are HIV-positive, and 311,701 are living with AIDS (includes only those cases where vital status is known). Of these patients, 44% are gay or bisexual men, 20% are heterosexual intravenous drug users, and 17% are women. In addition, approximately 1,000-2,000 children are born each year with HIV infection. The World Health Organization (WHO) estimates that 33 million adults and 1.3 million children worldwide were living with HIV/AIDS as of 1999 with 5.4 million being newly infected that year. Most of these cases are in the developing countries of Asia and Africa.

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Author Info: Rebecca J. Frey, The Gale Group Inc., Gale, Detroit, Gale Encyclopedia of Medicine, 2002
 
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