Generic Name:

zaleplon, Oral capsule

All Brands

  • Sonata
SECTION 1 of 5

Highlights for zaleplon

Oral capsule
ZALEPLON (ZAL e plon) is used to treat insomnia. This medicine helps you to fall asleep.
2 3 4
Talk to your healthcare provider if you have any of these conditions.
Know what to watch for and get tips for reducing your risks while taking this drug.
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zaleplon Side Effects

Oral capsule

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • changes in vision
  • confusion
  • depression, suicidal thoughts
  • feeling faint or lightheaded
  • hallucinations
  • hostility, restlessness, excitability
  • slurred speech
  • staggering, tremors
  • unusual activities while asleep like driving, eating, making phone calls
  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea
  • difficulty with coordination
  • loss of memory
  • nightmares
  • stomach upset
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zaleplon May Interact with Other Medications

Oral capsule
  • barbiturate medicines for inducing sleep or treating seizures
  • carbamazepine
  • certain medicines for allergies, like azatadine, clemastine, diphenhydramine
  • certain medicines for depression, anxiety, or other emotional or psychiatric problems
  • certain medicines for pain
  • cimetidine
  • erythromycin
  • medicines for fungal infections like ketoconazole, fluconazole, or itraconazole
  • other medicines given for sleep
  • phenytoin
  • rifampin
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
SECTION 4 of 5

How to Use zaleplon

Oral capsule

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. It is better to take this medicine on an empty stomach and only when you are ready for bed. Do not take your medicine more often than directed. If you have been taking this medicine for several weeks and suddenly stop taking it, you may get unpleasant withdrawal symptoms. Your doctor or health care professional may want to gradually reduce the dose. Do not stop taking this medicine on your own. Always follow your doctor or health care professional's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • depression
  • history of a drug or alcohol abuse problem
  • liver disease
  • lung or breathing disease
  • suicidal thoughts
  • an unusual or allergic reaction to zaleplon, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding
What if I miss a dose?

This does not apply. This medicine should only be taken immediately before going to sleep. Do not take double or extra doses.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Keep a regular sleep schedule by going to bed at about the same time each night. Avoid caffeine-containing drinks in the evening hours. When sleep medicines are used every night for more than a few weeks, they may stop working. Talk to your doctor if you still have trouble sleeping.

After taking this medicine for sleep, you may get up out of bed while not being fully awake and do an activity that you do not know you are doing. The next morning, you may have no memory of the event. Activities such as driving a car ("sleep-driving"), making and eating food, talking on the phone, sexual activity, and sleep-walking have been reported. Call your doctor right away if you find out you have done any of these activities. Do not take this medicine if you have used alcohol that evening or before bed or taken another medicine for sleep, since your risk of doing these sleep-related activities will be increased.

Do not take this medicine unless you are able to stay in bed for a full night (7 to 8 hours) before you must be active again. You may have a decrease in mental alertness the day after use, even if you feel that you are fully awake. Tell your doctor if you will need to perform activities requiring full alertness, such as driving, the next day. Do not stand or sit up quickly after taking this medicine, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

If you or your family notice any changes in your behavior, such as new or worsening depression, thoughts of harming yourself, anxiety, other unusual or disturbing thoughts, or memory loss, call your doctor right away.

After you stop taking this medicine, you may have trouble falling asleep. This is called rebound insomnia. This problem usually goes away on its own after 1 or 2 nights.

Where should I keep my medicine?

Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light. Throw away any unused medicine after the expiration date.

What does the pill look like?

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SECTION 5 of 5

How Much Does zaleplon Cost?

Oral capsule

We've partnered with GoodRx so you can compare prices, find discounts and save up to 80% on your next prescription. Check out the low coupon prices below — no insurance required.

Compare prices and save up to 80% on your next refill!

Lowest price for zaleplon

Target $18.82
Kroger Pharmacy $19.02
Kmart $19.02
These prices represent the lowest priced national pharmacies for zaleplon on GoodRx. They may be lower than your insurance.

Enter your zip code to find the best deal near you.

These prices represent the lowest priced national pharmacies for zaleplon on GoodRx. They may be lower than your insurance.

Last Updated: August 18, 2015

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