Highlights for trametinib
trametinib Side Effects
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- breathing problems
- changes in vision
- fast, irregular heartbeat
- feeling faint or lightheaded
- redness, swelling, or sores on hands or feet
- swelling of the ankles
Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):
- sore throat
- stomach pain
trametinib May Interact with Other Medications
Drug interactions have not been identified.
Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
How to Use trametinib
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 1 hour before or 2 hours after food. Do not take with food. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.
They need to know if you have any of these conditions:
- eye disease, vision problems
- heart disease
- high blood pressure
- kidney disease
- liver disease
- an unusual or allergic reaction to trametinib, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
If you miss a dose, take it as soon as you can. If your next dose is to be taken in less than 12 hours, then do not take the missed dose. Take the next dose at your regular time. Do not take double or extra doses.
Visit your doctor or health care professional for regular checks on your progress.
Tell your doctor or health care professional right away if you have any change in your eyesight.
Do not become pregnant while taking this medicine or for 4 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
In women, this medicine may interfere with the ability to have a child. You should talk with your doctor or health care professional if you are concerned about your fertility.
Store between 2 and 8 degrees C (36 and 46 degrees F). Do not freeze. Keep this medicine in the original container. Throw away any unused medicine after the expiration date.
Keep out of the reach of children.
Last Updated: June 11, 2013