Highlights for tolbutamide
tolbutamide Side Effects
Side effects that you should report to your doctor or health care professional as soon as possible:
- breathing difficulties
- dark yellow or brown urine or yellowing of the eyes or skin
- fever, chills, sore throat
- low blood sugar (ask your doctor or healthcare professional for a list of these symptoms)
- severe skin rash, redness, swelling or itching
- unusual bleeding or bruising
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
- nausea, vomiting
- stomach discomfort
tolbutamide May Interact with Other Medications
- medicines for fungal or yeast infections
Many medications may cause an increase or decrease in blood sugar, these include:
- alcohol containing beverages
- aspirin and aspirin-like drugs
- female hormones, like estrogens or progestins and birth control pills
- heart medicines
- male hormones or anabolic steroids
- medicines for weight loss
- medicines for allergies, asthma, cold, or cough
- medicines for mental problems
- medicines called MAO Inhibitors like Nardil, Parnate, Marplan, Eldepryl
- NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
- quinolone antibiotics like ciprofloxacin, levofloxacin, ofloxacin
- some herbal dietary supplements
- steroid medicines like prednisone or cortisone
- thyroid medicine
How to Use tolbutamide
Take this medicine by mouth. Swallow with a drink of water. Follow the directions on the prescription label. Take your medicine at the same time each day. Do not take more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Elderly patients over 65 years old may have a stronger reaction and need a smaller dose.
They need to know if you have any of these conditions:
- diabetic ketoacidosis
- glucose-6-phosphate dehydrogenase deficiency
- heart disease
- kidney disease
- liver disease
- severe infection or injury
- thyroid disease
- an unusual or allergic reaction to tolbutamide, sulfa drugs, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Visit your doctor or health care professional for regular checks on your progress.
A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.
Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.
Always carry a quick-source of sugar with you in case you have symptoms of low blood sugar. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once.
Tell your doctor or health care professional if you have high blood sugar. You might need to change the dose of your medicine. If you are sick or exercising more than usual, you might need to change the dose of your medicine.
Do not skip meals. Ask your doctor or health care professional if you should avoid alcohol. Many nonprescription cough and cold products contain sugar or alcohol. These can affect blood sugar.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Wear a medical ID bracelet or chain, and carry a card that describes your disease and details of your medicine and dosage times.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
What does the pill look like?
tolbutamide, Mylan Pharmaceuticals Inc., 500mg
tolbutamide, Mylan Institutional LLC, 500mg
Last Updated: April 2, 2014