Highlights for sapropterin
sapropterin Side Effects
Side effects that you should report to your doctor or health care professional as soon as possible:\n-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue\n-black or bloody stools, blood in the vomit\n-breathing problems\n-feeling faint or lightheaded, falls\n-hyperactivity, being fidgety or talking or moving around too much\n-severe abdominal pain\n \nSide effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):\n-cough\n-diarrhea\n-headache\n-nausea, vomiting\n-sore throat\n-runny or congested nose
sapropterin May Interact with Other Medications
\n -avanafil\n -levodopa\n -methotrexate\n -pemetrexed\n -pyrimethamine\n -sildenafil\n -tadalafil\n -vardenafil
How to Use sapropterin
Take this medicine by mouth with food. Follow the directions on the prescription label. Tablets may be swallowed whole or you may dissolve tablets in 4 to 8 ounces (120 to 240 ml) of water or apple juice. Drink within 15 minutes of mixing. To make tablets dissolve faster, you may crush or stir them. Tablets may not dissolve completely, and you may see small pieces floating in the glass. If small pieces remain in the glass after taking the medicine, add more water or apple juice to the glass and drink it to make sure you get all of the medicine. Tablets may also be crushed and then mixed in a small amount of apple sauce or pudding. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.\n \nTalk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 1 month of age for selected conditions, precautions do apply.
They need to know if you have any of these conditions:\n-eating disorder like anorexia, bulimia\n-fever\n-infection\n-kidney disease\n-liver disease\n-seizures\n-an unusual or allergic reaction to sapropterin, other medicines, foods, dyes, or preservatives\n-pregnant or trying to get pregnant\n-breast-feeding
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Your condition will be monitored carefully while you are receiving this medicine. Visit your doctor for regular check ups and for blood tests. It may take up to 4 weeks for your body to respond to this medicine.\n\nTell your doctor or health care professional if your symptoms do not start to get better or if they get worse.\n\nYou will need to be on a special diet while you are taking this medicine. Talk with your health care professional before making any changes to your diet.
Keep out of the reach of children.\n\nStore at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Store this medicine in the original container. Keep the container tightly closed. Throw away any unused medicine after the expiration date.
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Last Updated: May 14, 2014