Highlights for salsalate
salsalate Side Effects
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- black or bloody stools, blood in the urine or in vomit
- breathing problems
- changes in hearing, ringing in the ears
- chest pain
- general ill feeling or flu-like symptoms
- redness, blistering, peeling or loosening of the skin, including inside the mouth
- slurred speech or weakness on one side of the body
- unexplained weight gain or swelling
- unusually weak or tired
- yellowing of eyes or skin
- unusual bleeding or bruising
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
- stomach upset
salsalate May Interact with Other Medications
Do not take this medicine with any of the following medications:
This medicine may also interact with the following medications:
- aspirin and aspirin-like drugs
- bismuth subsalicylate
- medicines that treat or prevent blood clots like clopidel, ticlopidine, warfarin
- medicines for blood pressure
- NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
- varicella virus live vaccine
How to Use salsalate
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine with food if your stomach gets upset. Try to not lie down for at least 10 minutes after you take the medicine. Take your medicine at regular intervals. Do not take your medicine more often than directed.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Patients over 65 years old may have a stronger reaction and need a smaller dose.
They need to know if you have any of these conditions:
- drink more than 3 alcohol-containing drinks a day
- heart disease
- high blood pressure
- kidney disease
- liver disease
- stomach bleeding or ulcers
- an unusual or allergic reaction to salsalate, other salicylates, aspirin, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Tell your doctor or health care professional if your pain does not get better. Talk to your doctor before taking another medicine for pain. Do not treat yourself.
This medicine does not prevent heart attack or stroke. In fact, this medicine may increase the chance of a heart attack or stroke. The chance may increase with longer use of this medicine and in people who have heart disease. If you take aspirin to prevent heart attack or stroke, talk with your doctor or health care professional.
Do not take medicines such as aspirin, ibuprofen, and naproxen with this medicine. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many medicines available without a prescription should not be taken with this medicine.
This medicine can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Ulcers and bleeding can happen without warning symptoms and can cause death.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.
Last Updated: August 18, 2009