Highlights for regorafenib
regorafenib Side Effects
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- bloody or black, tarry stools
- breathing problems
- changes in vision
- chest pain or chest tightness
- feeling faint or lightheaded
- high fever
- light-colored stools
- nausea, vomiting
- red or dark-brown urine
- red spots on the skin
- right upper belly pain
- severe headache
- sores on the hands or feet
- spitting up blood or brown material that looks like coffee grounds
- stomach pain
- unusual bruising or bleeding from the eye, gums, or nose
- unusually weak or tired
- yellowing of the eyes or skin
Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):
- loss of appetite
- sore throat
- weight loss
regorafenib May Interact with Other Medications
This medicine may interact with the following:
- St. John's Wort
How to Use regorafenib
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not take it more often than directed. Take this medicine with food. Do not take with grapefruit juice. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
They need to know if you have any of these conditions:
- bleeding disorders
- heart disease
- high blood pressure
- liver disease
- recent surgery
- an unusual or allergic reaction to regorafenib, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
You may need blood work done while you are taking this medicine.
Do not become pregnant while taking this medicine or for 2 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 2 months after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
If you are going to have surgery or any other procedures, tell your doctor you are taking this medicine.
Talk to your doctor about your risk of cancer. You may be more at risk for certain types of cancers if you take this medicine.
Keep out of the reach of children.
Store between 20 and 25 degrees C (68 and 77 degrees F). Keep this medicine in the original container. Throw away any unused medicine after the expiration date.
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Last Updated: February 26, 2013