Promethazine tablet | Side Effects, Dosage, Uses & More
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Generic Name:

promethazine, Oral tablet

All Brands

  • Phenergan (Discontinued)
A discontinued drug is a drug that has been taken off the market due to safety issues, shortage of raw materials, or low market demand.
SECTION 1 of 5

Highlights for promethazine

Oral tablet
1

Promethazine hydrochloride is used for several reasons, including allergies, motion sickness, nausea and vomiting, sedation, anxiety and sleep before surgery, and pain and sleep after surgery.

2

This drug comes in the form of oral tablets, oral solution, and rectal suppositories.

3

The rectal suppository forms of this drug are available as the brand-named drugs Phenergan, Phenadoz, and Promethegan. All forms of the drug are available as generic drugs.

4

More common side effects of this drug include drowsiness, changes in blood pressure, skin reactions, reduced platelet counts, breathing problems, increased excitability or abnormal movements.

5

This drug can make you very drowsy. You shouldn’t drive, operate heavy machinery, or do activities that require you to be alert after you take this drug.

IMPORTANT INFORMATION

FDA warning

This drug has a black box warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients about drug effects that may be dangerous.

Warning for severe breathing problems in younger children. Promethazine hydrochloride should not be used in children younger than 2 years. In children this age, this drug may cause respiratory depression (slow breathing that does provide enough oxygen to the body) that may result in death. Caution should be used when giving this drug to children older than 2 years. Also, this drug should not be used in children who are taking other drugs that may cause respiratory depression.

Extreme drowsiness

This drug may cause extreme drowsiness that may impair your ability to ride a bike, drive a car, or operate machinery. 

Neuroleptic malignant syndrome

The use of this drug is associated with neuroleptic malignant syndrome. This is a potentially deadly syndrome with symptoms such as fever, muscle rigidity, mental changes, changes in pulse or blood pressure, fast heartbeat, increased sweating, or irregular heart rhythm.

What is promethazine hydrochloride?

Promethazine hydrochloride is a prescription drug. It’s available as an oral solution, a rectal suppository, and an oral tablet.

The rectal suppositories are available as the brand-named drugs Phenadoz, Phenergan, and Promethegan. They are also available as generic drugs. The oral solution and oral tablet are only available as generic drugs. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version.

This drug may be used as part of a combination therapy. This means you may need to take it with other medications.

Why it's used

Promethazine hydrochloride is used for several reasons, including allergies, motion sickness, nausea and vomiting, sedation, anxiety and sleep before surgery, and pain and sleep after surgery.

How it works

This drug belongs to two classes of drugs called antihistamines and antiemetics. A class of drugs is a group of medications that work in a similar way.

More Details

How it works

This drug belongs to two classes of drugs called antihistamines and antiemetics. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

It works by preventing the release of a substance called histamine from certain cells in your body. Histamine is normally released when you are exposed to things you are allergic to, like pollen, dander, mold, or other chemicals.

This drug also works to reduce stimulation of the part of your brain that sends signals to make you vomit.

By preventing the release of histamine, this drug causes sleepiness and helps with pain control. This is because histamine helps regulate wakefulness and helps to keep you alert and your senses heightened.

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SECTION 2 of 5

promethazine Side Effects

Oral tablet

More common side effects

Some of the more common side effects that can occur with use of promethazine hydrochloride include:

  • drowsiness

  • changes in blood pressure

  • allergic skin reactions

  • reduced platelet counts

  • reduced white blood cell production

  • breathing problems

  • increased excitability

  • abnormal movements

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious side effects

Call your doctor right away if you have serious side effects. Call 9-1-1 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • Extrapyramidal symptoms (uncontrollable movements). Symptoms can include:

    • uncontrollable upward staring, eye and lid twitching
    • uncontrollable neck muscle contractions causing your head to twist or turn to one side
    • sticking your tongue out uncontrollably
  • Seizures

  • Hallucination

  • Abnormal heart rhythm. Symptoms can include:

    • palpitations
    • dizziness
    • fainting
    • shortness of breath
    • chest pain
    • light headedness
  • Decreased platelet and white blood cell production. Symptoms can include:

    • bruising or abnormal bleeding. This includes bleeding from minor cuts, nose or mouth bleeding, and pinpoint red spots on your skin. It also includes abnormally heavy menstrual flow, blood in your urine, or black tarry stools.
    • fevers or infections
  • Severe breathing problems

  • Angioedema (buildup of fluid deep in your skin or underneath your skin). Symptoms can include:

    • swelling usually around your eyes and lips and sometimes your throat, hands, and feet.
    • swelling on the surface of your skin (welts)
    • painful and itchy welts (hives)
  • Neuroleptic malignant syndrome (a reaction to antipsychotic drugs that is sometimes fatal). Symptoms can include:

    • fever
    • muscle rigidity
    • mental changes
    • changes in pulse or blood pressure
    • fast heart rate
    • increased sweating
    • irregular heart rhythm
  • Jaundice. Symptoms can include:

    • yellow skin
    • yellowing of the whites of your eyes
    • dark or brown colored urine
    • yellowing of the inside of your mouth
    • pale or clay colored stools
Pharmacist's Advice
Clinical Associate Professor, University of Illinois at Chicago College of Pharmacy

This drug can cause extreme drowsiness.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
SECTION 3 of 5

promethazine May Interact with Other Medications

Oral tablet

Promethazine hydrochloride can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Alcohol interaction

Drinking alcohol can make drowsiness from promethazine hydrochloride more extreme and last longer. To avoid this, don’t drink alcohol while you are taking this drug.

Medications that might interact with this drug

Allergy drugs

When you take certain allergy drugs with promethazine hydrochloride, you may have increased side effects such as dry mouth, constipation, difficulty emptying your bladder, blurred vision, and drowsiness. These drugs include:

  • brompheniramine
  • carbinoxamine
  • chlorpheniramine
  • clemastine
  • cyproheptadine
  • diphenhydramine
  • hydroxyzine

Antidepressant drugs

If you take certain antidepressant drugs called monoamine oxidase inhibitors (MAOIs) with promethazine hydrochloride, you may increase your risk of extrapyramidal symptoms. These symptoms include uncontrollable upward staring, eye and lid twitching, uncontrollable neck muscle contractions (causing your head to twist or turn to one side), and sticking out your tongue uncontrollably. These drugs include: 

  • isocarboxazid
  • phenelzine
  • tranylcypromine 

When you take certain drugs called tricyclic antidepressants with promethazine hydrochloride, you may experience drowsiness that is more extreme and lasts longer. These drugs include:

  • amitriptyline
  • amoxapine
  • clomipramine
  • desipramine
  • doxepin
  • imipramine
  • nortriptyline
  • protriptyline
  • trimipramine

Anxiety drugs

When you take certain anxiety drugs with promethazine hydrochloride, you may experience drowsiness that is more extreme and lasts longer. These drugs include: 

  • alprazolam
  • chlordiazepoxide
  • clonazepam
  • clorazepate
  • diazepam
  • hydroxyzine
  • lorazepam
  • oxazepam

Bladder control drugs

When you take certain bladder control drugs with promethazine hydrochloride, side effects such as dry mouth, constipation, difficulty emptying your bladder, blurred vision, and drowsiness may be increased and last longer. These drugs include: 

  • darifenacin
  • flavoxate
  • oxybutynin
  • solifenacin
  • tolterodine
  • trospium

Muscle relaxants

When you take certain muscle relaxants with promethazine hydrochloride, you may experience drowsiness that is more extreme and lasts longer. These drugs include: 

  • baclofen
  • carisoprodol
  • chlorzoxazone
  • cyclobenzaprine
  • dantrolene
  • metaxalone
  • methocarbamol
  • orphenadrine
  • tizanidine

Nausea and motion sickness drugs

When you take certain nausea and motion sickness drugs with promethazine hydrochloride, side effects such as dry mouth, constipation, difficulty emptying your bladder, blurred vision, and drowsiness may be increased and last longer. These drugs include:

  • dimenhydrinate
  • meclizine
  • scopalamine

Pain drugs

When you take certain pain drugs with promethazine hydrochloride, you may experience drowsiness that is more extreme and lasts longer. These drugs include:

  • codeine
  • fentanyl
  • hydrocodone
  • hydromorphone
  • levorphanol
  • meperidine
  • methadone
  • morphine
  • oxycodone
  • oxymorphone
  • tramadol

Parkinson’s disease drugs

When you take certain Parkinson’s disease drugs with promethazine hydrochloride, side effects such as dry mouth, constipation, difficulty emptying your bladder, blurred vision, and drowsiness may be increased and last longer. These drugs include:

  • benztropine
  • trihexyphenidyl
  • amantadine

Seizure drugs

Taking phenobarbital with promethazine hydrochloride may lower levels of promethazine in your body. Promethazine may not work well at this lowered level.

Sleeping pills

When you take certain sleeping pills with promethazine hydrochloride, you may experience drowsiness that is more extreme and lasts longer. These drugs include: 

  • chloral hydrate
  • estazolam
  • eszopiclone
  • flurazepam
  • temazepam
  • triazolam
  • zaleplon
  • zolpidem

Stomach and gastrointestinal drugs

When you take certain stomach and gastrointestinal drugs with promethazine hydrochloride, side effects such as dry mouth, constipation, difficulty emptying your bladder, blurred vision, and drowsiness may be increased and last longer. These drugs include: 

  • belladonna alkaloids/phenobarbital
  • chlordiazepoxide/clinidium
  • dicyclomine
  • glycopyrrolate
  • hyoscyamine
  • methscopolamine
  • scopolamine

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
Promethazine hydrochloride warnings
angle-closure glaucoma
People with angle-closure glaucoma

Angle-closure glaucoma leads to increased pressure in your eye. If you have a history of angle-closure glaucoma, taking this drug may cause a sudden and severe increase in eye pressure. This is an emergency and may result in irreversible vision loss. Talk to your doctor before using this drug if you have this condition.

enlarged prostate
People with enlarged prostate

If you have difficulty urinating due to an enlarged prostate gland, taking this drug may worsen may make it even more difficult for you to urinate.

stomach problems
People with certain stomach problems

If you have a history of digestive tract blockage, taking this drug may make blockage worse because it slows down the movement through your digestive tract.

bladder problems
People with certain bladder problems

If you have a blockage in your bladder, taking this drug may make it more difficult for you to urinate. This is because it makes the tubes through which your urine flows narrower. This may make it even more difficult to empty your bladder.

bone marrow disease
People with bone marrow disease

This drug decreases your levels of platelets and white blood cells. You should not take it if you have bone marrow disease or you take other drugs that affect the ability of your bone marrow to make blood cells.

heart disease
People with heart disease

If you have heart disease, taking this drug may make it worse. This drug can cause the rhythm of your heart to be abnormal.

liver disease
People with liver disease

When your body gets rid of this drug, it first breaks it down in your liver.  If you have liver disease, your liver can’t break down the drug as quickly as it should. This means the level of this drug in your body could get too high. This can increase your risk of side effects.

breathing problems
People with breathing problems

This drug may thicken the secretions in your breathing tubes. If you have asthma or chronic obstructive pulmonary disease (COPD), this may cause an asthma attack or make your COPD worse. The drug should not be taken during an acute asthma attack or if you have COPD.

sleep apnea
People with sleep apnea

This drug may thicken the secretions in your breathing tubes. If you have sleep apnea, taking this drug at night may worsen your condition.

seizures
People with seizures

This drug can increase your risk of seizures. Talk to your doctor if you take other drugs that can cause seizures. Taking these drugs together can increase this risk.

Pregnant women
Pregnant women

Promethazine hydrochloride is a category C pregnancy drug. That means two things: 

  1. Research in animals has shown adverse effects to the fetus when the mother takes the drug.
  2. There haven’t been enough studies done in humans to be certain how the drug might affect the fetus. 

Talk to your doctor if you’re pregnant or planning to become pregnant. This drug should be used only if the potential benefit justifies the potential risk to the fetus. 

This drug should not be given to a pregnant woman within 2 weeks of delivery because it may cause an increased risk of bleeding. 

breast-feeding
Women who are breast-feeding

Promethazine hydrochloride may pass into breast milk and may cause side effects in a child who is breast-fed.

Talk to your doctor if you breast-feed your baby. You may need to decide whether to stop breast-feeding or stop taking this drug.

For seniors
For seniors

Seniors may be more sensitive to the sedating effects of this drug. They may be more likely to experience severe drowsiness, reduced mental alertness, and confusion.

For children
For children

This drug should not be used in children younger than 2 years. In children this age, this drug may cause respiratory depression (slow breathing that does provide enough oxygen to the body) that may result in death. Caution should be used when giving this drug to children older than 2 years. Also, this drug should not be used in children who are taking other drugs that may cause respiratory depression.

This drug is not recommended to treat uncomplicated vomiting in children. It should only be used for extended periods of vomiting when the cause is known. 

Some children who have taken this drug at the recommended dosages have had hallucinations and seizures. If children have a temporary illness, such as a cold or the flu, and take this drug, their risk of involuntary muscle contractions increases.

When to call the doctor
When to call the doctor

Call your doctor if your allergic reaction symptoms, nausea, motion sickness, or pain are not improving.

Allergies
Allergies

This drug can cause a severe allergic reaction. Symptoms can include: 

  • trouble breathing
  • swelling of your throat or tongue 

Call 9-1-1 or go to the nearest emergency room if you develop these symptoms. 

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

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How to Take promethazine (Dosage)

Oral tablet

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

What are you taking this medication for?

Allergies

Generic: promethazine

Form: Oral tablet
Strengths: 12.5 mg, 25 mg, 50 mg
Adult dosage (ages 18–64 years)
  • The average dose is 25 mg, taken at bedtime, or 12.5 mg, taken every 4 hours, right before meals.
  • The dose may be decreased by your doctor to the smallest amount that still works.
  • When using this drug to control allergic reactions to blood or plasma, the usual dose is 25 mg.
Child dosage (ages 2–17 years)
  • The average daily dose is 25 mg, taken at bedtime, or 12.5 mg, taken every 4 hours, right before meals.
  • The dose may be decreased by your doctor to the smallest amount that still works.
  • When using this drug to control allergic reactions to blood or plasma, the usual dose is 25 mg.
Child dosage (ages 0–23 months)

It has not been confirmed that promethazine hydrochloride is safe and effective for use in children younger than 2 years.

Senior dosage (ages 65 years and older)

The liver, kidneys, and hearts of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This increases your risk of side effects.

Your doctor may start you on a lower dose or a different medication schedule. This can help keep levels of this drug from building up too much in your body.

Warnings

Excessive large doses of this drug in children may cause sudden death.

Motion sickness

Generic: promethazine

Form: Oral tablet
Strengths: 12.5 mg, 25 mg, 50 mg
Adult dosage (ages 18–64 years)
  • The average dose is 25 mg, twice daily.
  • The initial dose should be taken ½–1 hour before travel. A second dose can be taken 8–12 hours later, if needed.
  • On the following days of travel, it is recommended to take 25 mg once you get up in the morning and again before your last meal of the day.
Child dosage (ages 2–17 years)
  • The average dose is 12.5–25 mg, twice daily.
  • The initial dose should be taken ½–1 hour before travel. A second dose can be taken 8–12 hours later, if needed.
  • On following days of travel, it is recommended to take 12.5–25 mg right after you get up in the morning and again before your last meal of the day.
Child dosage (ages 0–23 months)

It has not been confirmed that promethazine hydrochloride is safe and effective for use in children younger than 2 years.

Senior dosage (ages 65 years and older)

The liver, kidneys, and hearts of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This increases your risk of side effects.

Your doctor may start you on a lower dose or a different medication schedule. This can help keep levels of this drug from building up too much in your body.

Warnings

Excessive large doses of this drug in children may cause sudden death.

Nausea and vomiting

Generic: promethazine

Form: Oral tablet
Strengths: 12.5 mg, 25 mg, 50 mg
Adult dosage (ages 18–64 years)
  • For active nausea and vomiting, the average dose is 25 mg. Between 12.5 mg and 25 mg may be taken again every 4–6 hours, if needed.
  • For preventing nausea and vomiting, the average dose is 25 mg every 4–6 hours as needed.
Child dosage (ages 2–17 years)
  • For nausea and vomiting, the usual dose is 0.5 mg per kilogram of body weight.
  • The dose will be adjusted to age and weight of the child and severity of their condition.
Child dosage (ages 0–23 months)

It has not been confirmed that promethazine hydrochloride is safe and effective for use in children younger than 2 years.

Senior dosage (ages 65 years and older)

The liver, kidneys, and hearts of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This increases your risk of side effects.

Your doctor may start you on a lower dose or a different medication schedule. This can help keep levels of this drug from building up too much in your body.

Warnings

Excessive large doses of this drug in children may cause sudden death.

Sedation

Generic: promethazine

Form: Oral tablet
Strengths: 12.5 mg, 25 mg, 50 mg
Adult dosage (ages 18–64 years)

For sedation the usual dose is 25–50 mg.

Child dosage (ages 2–17 years)

For sedation, the usual dose is 12.5–25 mg.

Child dosage (ages 0–23 months)

It has not been confirmed that promethazine hydrochloride is safe and effective for use in children younger than 2 years.

Senior dosage (ages 65 years and older)

The liver, kidneys, and hearts of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This increases your risk of side effects.

Your doctor may start you on a lower dose or a different medication schedule. This can help keep levels of this drug from building up too much in your body.

Warnings

Excessive large doses of this drug in children may cause sudden death.

Anxiety and sleep aid before surgery

Generic: promethazine

Form: Oral tablet
Strengths: 12.5 mg, 25 mg, 50 mg
Adult dosage (ages 18–64 years)

The night before surgery, the usual dose is 50 mg to relieve anxiety and promote sleep.

Child dosage (ages 2–17 years)

The night before surgery, the usual dose is 12.5–25 mg to relieve anxiety and promote sleep.

Child dosage (ages 0–23 months)

It has not been confirmed that promethazine hydrochloride is safe and effective for use in children younger than 2 years.

Senior dosage (ages 65 years and older)

The liver, kidneys, and hearts of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This increases your risk of side effects.

Your doctor may start you on a lower dose or a different medication schedule. This can help keep levels of this drug from building up too much in your body.

Warnings

Excessive large doses of this drug in children may cause sudden death.

Pain and sleep aid after surgery

Generic: promethazine

Form: Oral tablet
Strengths: 12.5 mg, 25 mg, 50 mg
Adult dosage (ages 18–64 years)

After surgery, the usual dose is 25–50 mg to promote sleep and for use with other pain medications.

Child dosage (ages 2–17 years)

After surgery, the usual dose is 12.5–25 mg to promote sleep and for use with other pain medications.

Child dosage (ages 0–23 months)

It has not been confirmed that promethazine hydrochloride is safe and effective for use in children younger than 2 years.

Senior dosage (ages 65 years and older)

The liver, kidneys, and hearts of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This increases your risk of side effects.

Your doctor may start you on a lower dose or a different medication schedule. This can help keep levels of this drug from building up too much in your body.

Warnings

Excessive large doses of this drug in children may cause sudden death.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.
Pharmacist's Advice
Clinical Associate Professor, University of Illinois at Chicago College of Pharmacy

Promethazine hydrochloride comes with risks if you don’t take it as prescribed.

If you stop taking the drug or don’t take it at all

If you’re using this drug for allergies or an allergic reaction, your allergic symptoms such as sneezing, runny nose, itching, eye tearing, and hives may recur and worsen. If you are taking promethazine hydrochloride to prevent or treat nausea and vomiting, motion sickness, pain, or to lessen anxiety and promote sleep, you may not experience relief of your symptoms.

If you miss doses or don’t take the drug on schedule

Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

If you take too much

You could have dangerous levels of the drug in your body. If you think you’ve taken too much of the drug, act right away. Call your doctor or local poison control center, or go to the nearest emergency room.

What to do if you miss a dose

Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.

How to tell if the drug is working

If you’re using this drug for allergies or an allergic reaction, your symptoms, such as sneezing, runny nose, itching, eye tearing, and  hives, should decrease or stop. If you’re taking promethazine hydrochloride to prevent or treat nausea and vomiting, motion sickness, pain, or to lessen anxiety and promote sleep, you should experience relief of your symptoms.

Promethazine hydrochloride is used for short-term treatment.

Important considerations for taking promethazine hydrochloride

You can take this drug with or without food

Taking it with food may help to reduce upset stomach.

Do not store this drug in moist or damp areas

Store promethazine hydrochloride tablets at room temperature from 68ºF to 77ºF (20ºC to 25ºC). Keep it away from high temperatures and from the light.

A prescription for this medication is refillable

You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

  • Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
  • Don’t worry about airport x-ray machines. They can’t hurt your medication.
  • You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled box with you.
  • Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Sun sensitivity

This drug can make your skin more sensitive to the sun. This increases your risk of sunburn. Avoid the sun if you can. If you can’t, be sure to wear protective clothing and apply sunscreen.

Insurance

Some insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription.

Are there any alternatives?

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

SECTION 5 of 5

How Much Does promethazine Cost?

Oral tablet

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These prices represent the lowest priced national pharmacies for promethazine on GoodRx. They may be lower than your insurance.

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Content developed in collaboration with University of Illinois-Chicago, Drug Information Group

Medically reviewed by Creighton University, Center for Drug Information and Evidence-Based Practice on November 30, 2015

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
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