Pindolol | Side Effects, Dosage, Uses & More
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Generic Name:

pindolol, Oral tablet

Generic Name:

All Brands

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Highlights for pindolol

Oral tablet
1

Pindolol is used to treat hypertension (high blood pressure).

2

This drug comes in the form of a tablet you take by mouth.

3

You shouldn’t take this drug if you have certain types of asthma or heart failure or a very low heart rate.

4

More common side effects of taking this drug include trouble sleeping (insomnia), muscle pain, and dizziness.

5

Don’t suddenly stop taking pindolol. Stopping the medication suddenly can lead to serious heart problems.

IMPORTANT INFORMATION

Heart failure

Pindolol helps the heart from working as hard. In rare cases, this can lead to heart failure in people who have been on the drug for a long time.  Let your doctor know right away if you begin having symptoms of heart failure. These include shortness of breath, fatigue, and swelling in your legs.

Stopping the drug

Don’t abruptly stop taking pindolol. Stopping this drug suddenly can cause more angina (chest pain) or a heart attack. If you need to stop taking this drug, your doctor will slowly decrease your dose over 1–2 weeks. Your doctor will monitor you closely. If you develop chest pain or heart problems, you may need to start taking pindolol again, at least temporarily.

Surgery

Tell your doctor that you’re taking pindolol before you have any surgery. Your doctor will decide if you should keep taking pindolol or temporarily stop taking it before surgery. Follow the instructions of your doctor.

What is pindolol?

Pindolol is a prescription drug. It’s available as an oral tablet. 

Pindolol is only available as a generic drug. Generic drugs usually cost less. In some cases they may not be available in every strength or form as the brand. Talk to your healthcare provider to see if the generic will work for you.

Pindolol may be used as part of a combination therapy. This means you may need to take it with other medications. It is often used with water pills (thiazide diuretics).

Why it's used

Pindolol is used to treat high blood pressure.

How it works

Pindolol belongs to a class of drugs called beta blockers.

More Details

How it works

Pindolol belongs to a class of drugs called beta blockers. A class of drugs refers to medications that work similarly. They have a similar chemical structure and are often used to treat similar conditions.

Pindolol works by allowing the heart to beat slower and with less force. This lowers your blood pressure.

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pindolol Side Effects

Oral tablet

More Common Side Effects

Some of the more common side effects of pindolol include:

  • trouble sleeping

  • muscle pain

  • dizziness

  • swelling of your arms and legs

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious Side Effects

Call your doctor right away if you have serious side effects. Call 9-1-1 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • low heart rate

  • low blood pressure. Symptoms include:

    • feeling dizzy or like you might faint
  • breathing problems. Symptoms include:

    • shortness of breath
    • tightening of your airways
    • trouble breathing
    • wheezing
Pharmacist's Advice
Clinical Associate Professor, University of Illinois at Chicago College of Pharmacy

Pindolol may cause drowsiness. It may cause you to feel very tired the first few days that you take the medicine.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
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pindolol May Interact with Other Medications

Oral tablet

Pindolol can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. 

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Alcohol interaction

The use of drinks that contain alcohol can cause a sedative effect when you take this drug. You may have slowed reflexes, poor judgment, and sleepiness. This can be dangerous. If you drink alcohol, talk to your doctor.

Medications that might interact with this drug

Antipsychotic drugs

When pindolol is taken with certain antipsychotic medications, the amount of both drugs in your body can increase. This can lead to harmful side effects. 

These drugs include:

  • thioridazine
  • chlorpromazine
  • fluphenazine
  • perphenazine

High blood pressure and heart rate drugs

Taking these drugs with pindolol may increase your risk of a very low heart rate and blood pressure.

These drugs include:

  • nifedipine
  • diltiazem
  • verapamil
  • reserpine

Clonidine

Taking clonidine and pindolol may increase your risk of high blood pressure after you stop taking clonidine. If you take both drugs and then need to stop taking them, your doctor will have you stop taking pindolol several days before you slowly stop taking clonidine. If you’re replacing clonidine with pindolol, you should wait several days to start pindolol after stopping clonidine. 

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
Pindolol warnings
heart failure
People with heart failure

Pindolol may cause or worsen heart failure. This risk increases if you suddenly stop taking pindolol.

breathing problems
People with breathing problems

If you have an obstructive airway disease, pindolol may not be right for you. This medication can make it harder to breathe or stop certain breathing drugs from working as well. These include asthma, chronic bronchitis, and chronic obstructive pulmonary disease (COPD).

diabetes
People with diabetes

Pindolol can mask the signs of serious low blood sugar, such as a fast heart rate. This drug also lowers the amount of insulin your body releases in response to high blood sugar levels. If you have diabetes, your doctor may adjust your dose of your diabetes medicines.

thyroid disease
People with thyroid disease

Pindolol may mask the signs of high thyroid levels, such as a fast heart rate. Talk to your doctor if you have thyroid disease.

allergies
People with allergies

If you use epinephrine to treat your allergic reactions, it may not work as well. Pindolol may block some of epinephrine’s effect.

major surgery
People with plans to have major surgery

If you plan to have surgery, tell your doctor that you’re taking pindolol. This drug may increase your risk of complications during surgery or with general anesthesia. Your doctor will discuss with you whether to continue or stop the drug prior to surgery.

liver problems
People with liver problems

Pindolol is broken down in your liver. If you have liver problems, your doctor may lower your dose.

kidney problems
People with kidney problems

Pindolol is partly cleared from your body by your kidneys. If your kidneys don’t work well, your doctor may monitor you more closely.

Pregnant women
Pregnant women

Pindolol is a pregnancy category B drug. That means two things: 

  1. Research in animals has not shown a risk to the fetus when the mother takes the drug.
  2. There aren’t enough studies done in humans to show if the drug poses a risk to the fetus. 

Talk to your doctor if you’re pregnant or planning to become pregnant. Animal studies do not always predict the way humans would respond. Therefore, this drug should only be used in pregnancy if clearly needed.

breast-feeding
Women who are breast-feeding

Pindolol may pass into breast milk and may cause side effects in a child who is breastfed.

Talk to your doctor if you breastfeed your baby. You may need to decide whether to stop breastfeeding or stop taking this medication.

seniors
For seniors

The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This increases your risk of side effects.

children
For children

This medication hasn’t been studied in children and shouldn’t be used in children younger than 18 years.

allergies
Allergies

Pindolol can cause a severe allergic reaction. Symptoms can include:

  • rash
  • hives
  • shortness of breath
  • swelling of your tongue, lips, and face 

Call 9-1-1 or go to the nearest emergency room if you develop these symptoms. 

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

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How to Take pindolol (Dosage)

Oral tablet

All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

What are you taking this medication for?

Hypertension

Generic: pindolol

Form: Oral tablet
Strengths: 5 mg and 10 mg
Adult dosage (ages 18–64 years)

The starting dose is 5 mg taken by mouth twice per day. If your blood pressure stays high, your doctor may increase your dose to a maximum of 60 mg per day.

Child dosage (ages 0–17 years)

This medicine hasn’t been studied in children and shouldn’t be used in children younger than 18 years.

Senior dosage (ages 65 years and older)

The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This increases your risk of side effects.

Your doctor may start you on a lowered dose or a different medication schedule. This can help keep levels of this drug from building up too much in your body.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.
Pharmacist's Advice
Clinical Associate Professor, University of Illinois at Chicago College of Pharmacy

Pindolol comes with serious risks if you don't take it as prescribed.

If you don't take it at all

If you decide not to take this medication, your blood pressure may get worse. You have a higher chance of a heart attack or stroke.

If you stop taking it suddenly

Don’t stop taking pindolol suddenly. This could increase your risk of heart failure, angina (chest pain), or a heart attack.

If you miss doses or don’t take the drug on schedule

Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

If you take too much

You could have dangerous levels of the drug in your body. This may cause:

  • very low heart rate or blood pressure
  • trouble breathing
  • heart failure

If you think you’ve taken too much of the drug, act right away. Call your doctor or local poison control center, or go to the nearest emergency room.

What to do if you miss a dose

Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.

How to tell if the drug is working

You’ll be able to tell if this drug is working if you check your blood pressure and it’s lower.

Pindolol is used for long-term treatment.

Important considerations for taking pindolol
taken with or without food
Pindolol can be taken with or without food
Don’t crush
Don’t crush, break, or chew pindolol tablets
storage
Store pindolol at room temperature
See Details
medication is refillable
A prescription for this medication is refillable
See Details
Travel
Travel
See Details
Self-management
Self-management
See Details
clinical monitoring
Clinical monitoring
See Details
not usually stocked
Not every pharmacy stocks this drug. When filling your prescription, be sure to call ahead
prior authorization
Insurance
See Details

Store pindolol at room temperature

Keep it from 68°F to 77°F (20°C to 25°C). Keep it away from light and high temperatures. 

Don’t store this medication in moist or damp areas, such as bathrooms.

A prescription for this medication is refillable

You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

  • Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
  • Don’t worry about airport x-ray machines. They can’t hurt your medication.
  • You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled box with you.
  • Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Self-management

You may need to check your blood pressure at home. You may need to buy a home blood pressure monitor to do this. These are available at most pharmacies. You should keep a log with the date, time of day, and your blood pressure readings. Bring this diary with you to your doctor appointments.

Clinical monitoring

While you are taking pindolol your doctor will monitor certain health issues. This can help make sure you stay safe while you take this drug. These issues include:

  • heart rate
  • blood pressure
  • lung function
  • liver function
  • kidney function

Insurance

You may need to buy a home blood pressure monitor.

Are there any alternatives?

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

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How Much Does pindolol Cost?

Oral tablet

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Lowest price for pindolol

Walmart $20.19
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Walgreens $35.97
These prices represent the lowest priced national pharmacies for pindolol on GoodRx. They may be lower than your insurance.

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These prices represent the lowest priced national pharmacies for pindolol on GoodRx. They may be lower than your insurance.

Content developed in collaboration with University of Illinois-Chicago, Drug Information Group

Medically reviewed by Creighton University, Center for Drug Information and Evidence-Based Practice on October 13, 2015

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
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