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Generic Name:

nedocromil, Ophthalmic solution

All Brands

  • Alocril
SECTION 1 of 5

Highlights for nedocromil

Ophthalmic solution
1

Nedocromil sodium is used to treat itching of inflamed eyes caused by allergies.

2

This drug comes in the form of a solution you drop into your eye.

3

Nedocromil is available as a brand-name drug called Alocril. It’s also available as a generic drug.

4

The more common side effects of this drug include headache and burning, stinging, or irritation in your eye. They also include an unpleasant taste in your mouth, stuffy nose, symptoms of asthma, redness and inflammation of your eye, and eye sensitivity to light.

5

You shouldn’t wear contact lenses while using nedocromil eye drops. Be careful not to let the dropper tip of the eye drops touch your eye when giving yourself the medication.

IMPORTANT INFORMATION

Use of contact lenses

You shouldn’t wear contact lenses while taking this drug. If your eyes are inflamed and itchy, you shouldn’t wear contact lenses.

Contamination of dropper tip and solution

Be careful not to let the dropper tip of the eye drops touch your eye, eyelids, or surrounding areas when giving yourself the medication. This could contaminate the dropper tip and the solution.

What is nedocromil?

Nedocromil is a prescription drug. It’s available as an ophthalmic solution (eye drop).

Nedocromil is available as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version. Talk to your doctor to see if the generic version will work for you.

Nedocromil may be used as part of a combination therapy. This means you may need to take it with other medications.

Why it's used

Nedocromil eye drops are used to treat itching of inflamed eyes caused by allergies.

How it works

Nedocromil belongs to a class of drugs called mast cell stabilizers.

More Details

How it works

Nedocromil belongs to a class of drugs called mast cell stabilizers. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Nedocromil works by stopping the release of mediators, such as histamine and eosinophils, that cause allergies in your body. This reduces your symptoms of allergies, including itchy and inflamed eyes.

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nedocromil Side Effects

Ophthalmic solution

More Common Side Effects

The more common side effects of nedocromil include:

  • headache

  • burning, stinging, or irritation in your eye

  • unpleasant taste in your mouth

  • stuffy nose

  • symptoms of asthma, such as shortness of breath or wheezing

  • redness and inflammation of your eye

  • eye sensitivity to light

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Pharmacist's Advice
Clinical Associate Professor, University of Illinois at Chicago College of Pharmacy

Nedocromil doesn’t cause drowsiness.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
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nedocromil May Interact with Other Medications

Ophthalmic solution

An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help prevent interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking.

To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Talk to your doctor before using this drug with other eye medications.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
Nedocromil sodium warnings
People with asthma or chronic obstructive pulmonary disease
People with asthma or chronic obstructive pulmonary disease

This drug may cause wheezing or shortness of breath. You shouldn’t use it if you’re having an asthma attack or trouble breathing because it may make it worse. If you have a history of asthma or chronic obstructive pulmonary disease (COPD), talk to your doctor about whether this drug is safe for you.

Pregnant women
Pregnant women

Nedocromil is a category B pregnancy drug. That means two things:

  • Research in animals hasn’t shown a risk to the fetus when the mother takes the drug.
  • There aren’t enough studies done in humans to show if the drug poses a risk to the fetus.

Talk to your doctor if you’re pregnant or planning to become pregnant. Animal studies don’t always predict the way humans would respond. Therefore, this drug should only be used in pregnancy if clearly needed.

Women who are breast-feeding
Women who are breast-feeding

Nedocromil may pass into breast milk and may cause side effects in a child who is breast-fed.

Talk to your doctor if you breast-feed your child. You may need to decide whether to stop breast-feeding or stop taking this medication.

For children
For children

This medication hasn’t been studied and shouldn’t be used in children younger than 3 years.

When to call the doctor
When to call the doctor

Call your doctor if the itching in your eyes doesn’t improve after using nedocromil for a few weeks.

Allergies
Allergies

Nedocromil can cause a severe allergic reaction. Symptoms can include:

  • hives
  • rash
  • swelling of your tongue, lips, or face
  • trouble breathing

If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 9-1-1 or go to the nearest emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

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How to Take nedocromil (Dosage)

Ophthalmic solution

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

What are you taking this medication for?

Itching of inflamed eyes due to allergies

Brand 1: Alocril

Form: ophthalmic solution 2%

Generic: Nedocromil sodium

Form: ophthalmic solution 2%
Adult dosage (ages 18 years and older):

Instill (drop) 1–d drops in each eye two times per day.

Child dosage (ages 3–17 years):

Instill (drop) 1–d drops in each eye two times per day.

Child Dosage (ages 0–2 years):

This medication hasn’t been studied and shouldn’t be used in children younger than 3 years.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.
Pharmacist's Advice
Clinical Associate Professor, University of Illinois at Chicago College of Pharmacy

Nedocromil comes with risks if you don’t take it as prescribed.

If you stop taking the drug or don’t take it at all

Your eye itching may get worse or may no longer stay controlled.

If you miss doses or don’t take the drug on schedule

Your medication may not work as well or may stop working completely.

What to do if you miss a dose

Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.

If you take too much

You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include:

  • wheezing
  • trouble breathing

If you think you have instilled too much of the drug, call your doctor or local poison control center. If your symptoms are severe, call 9-1-1 or go to the nearest emergency room right away.

How to tell if the drug is working

Your eyes should be less itchy.

Nedocromil is used for short-term treatment.

Store nedocromil at room temperature or in the refrigerator

Keep it between 36°F and 77°F (2°C and 25°C).

A prescription for this medication is refillable

You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

  • Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
  • Don’t worry about airport x-ray machines. They can’t hurt your medication.
  • You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled box with you.
  • Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Self-management

You should read the package insert before using the eye drops.

To use the drops:

  • First, wash your hands.
  • Tilt your head back, look up with your eyes, and draw the lower lid of your eye down using your index finger.
  • Squeeze the number of prescribed drops into your eye without touching the dropper tip to the eye. Blink a few times. Repeat the same steps for the other eye.

Insurance

Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription.

Are there any alternatives?

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

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How Much Does nedocromil Cost?

Ophthalmic solution

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Lowest price for nedocromil

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These prices represent the lowest priced national pharmacies for nedocromil on GoodRx. They may be lower than your insurance.

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Content developed in collaboration with University of Illinois-Chicago, Drug Information Group

Medically reviewed by Creighton University, Center for Drug Information and Evidence-Based Practice on November 15, 2015

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
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