Highlights for milnacipran
milnacipran Side Effects
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- chest pain, fast or irregular heartbeat
- fever or chills, sore throat
- hallucination, loss of contact with reality
- increase in blood pressure
- redness, blistering, peeling or loosening of the skin, including inside the mouth
- suicidal thoughts or other mood changes
- talking fast and having excited feelings or actions that are out of control
- trouble passing urine or change in the amount of urine
- unusual bleeding or bruising
- unusually weak or tired
- yellowing of the eyes, skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
- blurred vision
- change in sex drive or performance
- dry mouth
- increased sweating
- trouble sleeping
milnacipran May Interact with Other Medications
Do not take this medicine with any of the following medications:
medicines called MAO Inhibitors like Nardil, Parnate, Marplan, Eldepryl
- methylene blue
This medicine may also interact with the following medications:
amphetamine or dextroamphetamine
aspirin and aspirin-like medicines
medicines for blood pressure
medicines for migraine headache like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin
NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen
other medicines for depression, anxiety, or psychotic disturbances
St. John's wort, Hypericum perforatum
How to Use milnacipran
Take this medicine by mouth with a glass of water. You can take it with or without food. If it upsets your stomach, take it with food. Follow the directions on the prescription label. Do not take your medicine more often than directed. Do not stop taking this medicine suddenly except upon the advice of your doctor. Stopping this medicine too quickly may cause serious side effects or your condition may worsen.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
They need to know if you have any of these conditions:
- bleeding disorders
- heart disease
- high blood pressure
- if you often drink alcohol
- irregular heart beat
- kidney disease
- liver disease
- mania or bipolar disorder
- prostate disease
- suicidal thoughts, plans, or attempt; a previous suicide attempt by you or a family member
- taken an MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate within 14 days
- an unusual or allergic reaction to milnacipran, levomilnacipran, other medicines, foods, or preservatives
- pregnant or trying to get pregnant
If you miss a dose, skip that dose and take the next dose at your regular time. Do not take double or extra doses.
Tell your doctor if your symptoms do not get better or if they get worse. Visit your doctor or health care professional for regular checks on your progress.
Patients and their families should watch out for new or worsening thoughts of suicide or depression. Also watch out for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of treatment or after a change in dose, call your health care professional.
This medicine can cause an increase in blood pressure. Check with your doctor for instructions on monitoring your blood pressure while taking this medicine.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Your mouth may get dry. Chewing sugarless gum, sucking hard candy and drinking plenty of water will help. Contact your doctor if the problem does not go away or is severe.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
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Last Updated: February 10, 2015