Generic Name: milnacipran, Oral tablet

Generic Name:

milnacipran, Oral tablet

Savella

All Brands

  • Savella
SECTION 1 of 5

Highlights for milnacipran

Oral tablet
1
MILNACIPRAN (mil NA si pran) is used to treat the pain caused by fibromyalgia.
2 3 4
Talk to your healthcare provider if you have any of these conditions.
5
Know what to watch for and get tips for reducing your risks while taking this drug.
SECTION 2 of 5

milnacipran Side Effects

Oral tablet

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • chest pain, fast or irregular heartbeat
  • confusion
  • fever or chills, sore throat
  • hallucination, loss of contact with reality
  • increase in blood pressure
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • seizures
  • suicidal thoughts or other mood changes
  • talking fast and having excited feelings or actions that are out of control
  • trouble passing urine or change in the amount of urine
  • unusual bleeding or bruising
  • unusually weak or tired
  • yellowing of the eyes, skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • blurred vision
  • change in sex drive or performance
  • constipation
  • dry mouth
  • flushing
  • headache
  • increased sweating
  • nausea
  • trouble sleeping
SECTION 3 of 5

milnacipran May Interact with Other Medications

Oral tablet

Do not take this medicine with any of the following medications:

  • linezolid

medicines called MAO Inhibitors like Nardil, Parnate, Marplan, Eldepryl

  • methylene blue

tryptophan

This medicine may also interact with the following medications:

amphetamine or dextroamphetamine

aspirin and aspirin-like medicines

clonidine

digoxin

epinephrine

furazolidone

lithium

medicines for blood pressure

medicines for migraine headache like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan

medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin

NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen

other medicines for depression, anxiety, or psychotic disturbances

procarbazine

St. John's wort, Hypericum perforatum

tramadol

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
SECTION 4 of 5

How to Use milnacipran

Oral tablet

Take this medicine by mouth with a glass of water. You can take it with or without food. If it upsets your stomach, take it with food. Follow the directions on the prescription label. Do not take your medicine more often than directed. Do not stop taking this medicine suddenly except upon the advice of your doctor. Stopping this medicine too quickly may cause serious side effects or your condition may worsen.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • bleeding disorders
  • glaucoma
  • heart disease
  • high blood pressure
  • if you often drink alcohol
  • irregular heart beat
  • kidney disease
  • liver disease
  • mania or bipolar disorder
  • prostate disease
  • seizures
  • suicidal thoughts, plans, or attempt; a previous suicide attempt by you or a family member
  • taken an MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate within 14 days
  • an unusual or allergic reaction to milnacipran, levomilnacipran, other medicines, foods, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding
What if I miss a dose?

If you miss a dose, skip that dose and take the next dose at your regular time. Do not take double or extra doses.

What should I watch for while using this medicine?

Tell your doctor if your symptoms do not get better or if they get worse. Visit your doctor or health care professional for regular checks on your progress.

Patients and their families should watch out for new or worsening thoughts of suicide or depression. Also watch out for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of treatment or after a change in dose, call your health care professional.

This medicine can cause an increase in blood pressure. Check with your doctor for instructions on monitoring your blood pressure while taking this medicine.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Your mouth may get dry. Chewing sugarless gum, sucking hard candy and drinking plenty of water will help. Contact your doctor if the problem does not go away or is severe.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

What does the pill look like?

Showing - out of 4
SECTION 5 of 5

How Much Does milnacipran Cost?

Oral tablet
We've partnered with GoodRX so you can compare prices and save money on your next prescription. Check out the lowest cash prices below and enter your zip code to find the best deal near you.

Compare prices and save money on your next refill!

Lowest price for milnacipran

Membership warehouse $236.24
Kroger Pharmacy $237.15
Publix $237.18
These represent the lowest cash prices for milnacipran and may be lower than your insurance.

Find the lowest prices of milnacipran near you

These represent the lowest cash prices for milnacipran and may be lower than your insurance.

Last Updated: February 10, 2015

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