Generic Name: mifepristone, Oral tablet

Korlym,Mifeprex

All Brands

  • Korlym
  • Mifeprex
SECTION 1 of 4

Highlights for mifepristone

Oral tablet
1
MIFEPRISTONE (mi FE pri stone) is a hormone-like drug. It is used in combination with other medicines to end an early pregnancy (usually during the first 7 weeks). This medicine is only available in a doctor's office, health clinic, or hospital.
2 3 4
Talk to your healthcare provider if you have any of these conditions.
5
Know what to watch for and get tips for reducing your risks while taking this drug.
SECTION 2 of 4

mifepristone Side Effects

Oral tablet

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • fast, irregular heartbeat
  • feeling faint, lightheaded
  • fever
  • stomach pain
  • unusually weak or tired
  • vaginal discharge with bad smell

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • back pain
  • diarrhea
  • headache
  • loss of appetite
  • nausea, vomiting
  • stomach cramps
  • vaginal bleeding
SECTION 3 of 4

mifepristone May Interact with Other Medications

Oral tablet

Do not take this medicine with any of the following medications:

-certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole

-certain medicines that treat or prevent blood clots like enoxaparin, warfarin

-cerivastatin

-cisapride

-dofetilide

-dronedarone

-pimozide

-ranolazine

-steroid medicines like prednisone or cortisone

-thioridazine

-ziprasidone

This medicine may also interact with the following medications:

-certain medicines for seizures like carbamazepine, phenytoin, phenobarbital

-certain medicines used in surgery for anesthesia

-erythromycin

-grapefruit juice

-other medicines that prolong the QT interval (cause an abnormal heart rhythm)

-rifampin

-St. John's wort or other herbal products

SECTION 4 of 4

How to Use mifepristone

Oral tablet

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Before you take this medicine, read the information your doctor or health care provider gives you. Talk to your doctor about any questions you have. Take your medicine exactly as directed. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • adrenal gland problems
  • bleeding problems
  • cannot easily get emergency medical help in the 2 weeks after you take this medicine
  • cannot return for follow up appointments after you take this medicine
  • have intrauterine device (IUD)
  • it has been more than 49 days (7 weeks) since your last menstrual period began
  • other medical problem
  • porphyria
  • take medicines that treat or prevent blood clots like enoxaparin, warfarin
  • take steroid medicines like prednisone or cortisone
  • tubal or ectopic pregnancy
  • an unusual or allergic reaction to mifepristone, misoprostol, prostaglandins, or other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding
What if I miss a dose?

This does not apply.

What should I watch for while using this medicine?

For your safety, you must visit your doctor as directed after taking this medicine. Report any unusual effects to your doctor. This medicine can cause birth defects. You will need surgery if this medicine fails to cause a full abortion.

After you take this medicine, some vaginal bleeding is normal. Heavy bleeding may be a sign that something is wrong. If you soak through 2 thick full-size sanitary pads each hour for 2 hours, get medical help right away. Tell the health care provider that you have taken this medicine.

Call your doctor if you have a fever, stomach pain or tenderness, nausea, vomiting, diarrhea, or feel weak. This may be a sign that something is wrong. You may have a serious infection or complication and need medical help.

Keep the MedGuide for this medicine. If you need emergency medical care, show your healthcare provider the MedGuide.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

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Last Updated: January 15, 2014

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