Highlights for metformin-pioglitazone
metformin-pioglitazone Side Effects
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- blood in the urine
- breathing problems
- dark urine
- feeling faint or lightheaded, falls
- fever, chills
- increased urination
- muscle aches, pains
- pain when urinating
- signs and symptoms of low blood sugar such as feeling anxious, confusion, dizziness, increased hunger, unusually weak or tired, sweating, shakiness, cold, irritable, headache, blurred vision, fast heartbeat, loss of consciousness
- slow or irregular heartbeat
- stomach pain
- swelling of the hands, legs, or feet
- yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
- sore throat
- stuffy or runny nose
- stomach gas, upset
metformin-pioglitazone May Interact with Other Medications
Do not take this medicine with any of the following medications:
- certain contrast medicines given before X-rays, CT scans, MRI, or other procedures
This medicine may also interact with the following medications:
- female hormones, like estrogens or progestins and birth control pills
- medicines for blood pressure, heart disease, irregular heart beat
- phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
- steroid medicines like prednisone or cortisone
- thyroid hormones
How to Use metformin-pioglitazone
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine with food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
They need to know if you have any of these conditions:
- become easily dehydrated
- bladder cancer
- diabetic ketoacidosis
- heart disease
- if you frequently drink alcohol containing drinks
- kidney disease
- liver disease
- polycystic ovary syndrome
- serious infection or injury
- swelling of the arms, legs, or feet
- undergoing surgery or certain x-ray procedures with injectable contrast agents
- an unusual or allergic reaction to metformin, pioglitazone, medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Visit your doctor or health care professional for regular checks on your progress.
A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.
Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.
Always carry a quick-source of sugar with you in case you have symptoms of low blood sugar. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once.
Tell your doctor or health care professional if you have high blood sugar. You might need to change the dose of your medicine. If you are sick or exercising more than usual, you might need to change the dose of your medicine.
Do not skip meals. Ask your doctor or health care professional if you should avoid alcohol. Many nonprescription cough and cold products contain sugar or alcohol. These can affect blood sugar.
If you need surgery or if you will need a procedure with contrast drugs, tell your doctor or health care professional that you are taking this medicine.
Wear a medical ID bracelet or chain, and carry a card that describes your disease and details of your medicine and dosage times.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture and light. Throw away any unused medicine after the expiration date.
Last Updated: April 1, 2014