Generic Name: melatonin, Oral capsule

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Highlights for melatonin

Oral capsule
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MELATONIN (mel uh TOH nin) is a dietary supplement. It is promoted to help maintain normal sleep patterns. The FDA has not approved this supplement for any medical use. This supplement may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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This drug also comes in other forms, including Oral SolutionOrally disintegrating solidOral tabletSublingual tablet
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Talk to your healthcare provider if you have any of these conditions.
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Know what to watch for and get tips for reducing your risks while taking this drug.
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melatonin Side Effects

Oral capsule

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • confusion, forgetful
  • depressed, nervous, or other mood changes
  • fast or pounding heartbeat
  • trouble staying awake or alert during the day

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • drowsiness, dizziness
  • headache
  • nightmares
  • upset stomach
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melatonin May Interact with Other Medications

Oral capsule

Check with your doctor or healthcare professional if you are taking any of the following medications:

  • hormone medicines
  • medicines for blood pressure like nifedipine
  • medications for anxiety, depression, or other emotional or psychiatric problems
  • medications for seizures
  • medications for sleep
  • other herbal or dietary supplements
  • tamoxifen
  • treatments for cancer or immune disorders
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
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How to Use melatonin

Oral capsule

Take this supplement by mouth with a glass of water. This supplement is usually taken prior to bedtime. Do not chew or crush most tablets or capsules. Some tablets are chewable and are chewed before swallowing. Some tablets are meant to be dissolved in the mouth or under the tongue. Follow the directions on the package labeling, or take as directed by your health care professional. Do not take this supplement more often than directed.

Talk to your pediatrician regarding the use of this supplement in children. This supplement is not recommended for use in children.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • cancer
  • if you frequently drink alcohol containing drinks
  • immune system problems
  • liver disease
  • seizure disorder
  • an unusual or allergic reaction to melatonin, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding
What if I miss a dose?

This does not apply; this medicine is not for regular use. Do not take double or extra doses.

What should I watch for while using this medicine?

See your doctor if your symptoms do not get better or if they get worse. Do not take this supplement for more than 2 weeks unless your doctor tells you to.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Talk to your doctor before you use this supplement if you are currently being treated for an emotional, mental, or sleep problem. This medicine may interfere with your treatment.

Herbal or dietary supplements are not regulated like medicines. Rigid quality control standards are not required for dietary supplements. The purity and strength of these products can vary. The safety and effect of this dietary supplement for a certain disease or illness is not well known. This product is not intended to diagnose, treat, cure or prevent any disease.

The Food and Drug Administration suggests the following to help consumers protect themselves:

  • Always read product labels and follow directions.
  • Natural does not mean a product is safe for humans to take.
  • Look for products that include USP after the ingredient name. This means that the manufacturer followed the standards of the US Pharmacopoeia.
  • Supplements made or sold by a nationally known food or drug company are more likely to be made under tight controls. You can write to the company for more information about how the product was made.
Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature or as directed on the package label. Protect from moisture. Throw away any unused supplement after the expiration date.

What does the pill look like?

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Last Updated: October 31, 2014

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