Generic Name: levothyroxine, Oral capsule

Tirosint

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  • Tirosint
SECTION 1 of 5

Highlights for levothyroxine

Oral capsule
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LEVOTHYROXINE (lee voe thye ROX een) is a thyroid hormone. This medicine can improve symptoms of thyroid deficiency such as slow speech, lack of energy, weight gain, hair loss, dry skin, and feeling cold. It also helps to treat goiter (an enlarged thyroid gland). It is also used to treat some kinds of thyroid cancer along with surgery and other medicines.
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This drug also comes in other forms, including Parenteral SolutionOral tablet
3 4 5
Talk to your healthcare provider if you have any of these conditions.
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Know what to watch for and get tips for reducing your risks while taking this drug.
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levothyroxine Side Effects

Oral capsule

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • chest pain
  • excessive sweating or intolerance to heat
  • fast or irregular heartbeat
  • nervousness
  • swelling of ankles, feet, or legs
  • tremors

Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):

  • changes in appetite
  • changes in menstrual periods
  • diarrhea
  • hair loss
  • headache
  • trouble sleeping
  • weight loss
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levothyroxine May Interact with Other Medications

Oral capsule
  • amiodarone
  • antacids
  • anti-thyroid medicines
  • calcium supplements
  • carbamazepine
  • cholestyramine
  • colestipol
  • digoxin
  • female hormones, including contraceptive or birth control pills
  • iron supplements
  • ketamine
  • liquid nutrition products like Ensure
  • medicines for colds and breathing difficulties
  • medicines for diabetes
  • medicines for mental depression
  • medicines or herbals used to decrease weight or appetite
  • phenobarbital or other barbiturate medications
  • phenytoin
  • prednisone or other corticosteroids
  • rifabutin
  • rifampin
  • simethicone
  • sodium polystyrene sulfonate
  • soy isoflavones
  • sucralfate
  • theophylline
  • warfarin
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
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How to Use levothyroxine

Oral capsule

Take this medicine by mouth with a glass of water. It is best to take on an empty stomach, at least 30 minutes to one hour before breakfast. Avoid taking antacids containing aluminum or magnesium, simethicone, bile acid sequestrants, calcium carbonate, sodium polystyrene sulfonate, ferrous sulfate, and sucralfate within 4 hours of taking this medicine. Do not cut, crush or chew this medicine. Follow the directions on the prescription label. Take at the same time each day. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply. Since the capsules cannot be crushed or placed in water, they may only be given to infants and children who are able to swallow an intact capsule.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • angina
  • blood clotting problems
  • diabetes
  • dieting or on a weight loss program
  • fertility problems
  • heart disease
  • high levels of thyroid hormone
  • pituitary gland problem
  • previous heart attack
  • an unusual or allergic reaction to levothyroxine, thyroid hormones, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding
What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What should I watch for while using this medicine?

Do not switch brands of this medicine unless your health care professional agrees with the change. Ask questions if you are uncertain.

You will need regular exams and occasional blood tests to check the response to treatment. If you are receiving this medicine for an underactive thyroid, it may be several weeks before you notice an improvement. Check with your doctor or health care professional if your symptoms do not improve.

It may be necessary for you to take this medicine for the rest of your life. Do not stop using this medicine unless your doctor or health care professional advises you to.

This medicine can affect blood sugar levels. If you have diabetes, check your blood sugar as directed.

You may lose some of your hair when you first start treatment. With time, this usually corrects itself.

If you are going to have surgery, tell your doctor or health care professional that you are taking this medicine.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Keep container tightly closed. Throw away any unused medicine after the expiration date.

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How Much Does levothyroxine Cost?

Oral capsule
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Lowest price for levothyroxine

These represent the lowest cash prices for levothyroxine and may be lower than your insurance.

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These represent the lowest cash prices for levothyroxine and may be lower than your insurance.

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Last Updated: March 11, 2010

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