Indacaterol | Side Effects, Dosage, Uses & More
Advertisement

Generic Name:

indacaterol, Inhalation powder

All Brands

  • ARCAPTA NEOHALER
SECTION 1 of 5

Highlights for indacaterol

Inhalation powder
1

Indacaterol is a long-acting bronchodilator that opens up the airways in your lungs. It’s used to treat chronic obstructive pulmonary disease (COPD). This condition causes symptoms such as wheezing, cough, chest tightness, and shortness of breath.

2

This drug is available as an inhalation powder in capsules you take by mouth.

3

Indacaterol isn’t available as a generic drug. It’s only available as brand-named drug Arcapta Neohaler.

4

More common side effects of taking this drug include runny nose, cough, sore throat, headache, and nausea.

5

This drug shouldn’t be used to treat sudden symptoms of COPD. Always have your rescue inhaler, such as albuterol, with you to treat sudden symptoms. If you don’t have a rescue inhaler, ask your doctor to prescribe one to you.

IMPORTANT INFORMATION

FDA warning

This drug has a black box warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients about drug effects that may be dangerous.

Asthma-related death warning. People with asthma who take long-acting beta2-adrendergic agonist (LABA) drugs, such as this drug, have an increased risk of death from asthma problems. It isn’t known if LABA medicines, such as this drug, increase the risk of death in people with COPD. Get emergency medical help right away if your breathing problems worsen quickly, or if you use your rescue inhaler medicine but it doesn’t relieve your symptoms.

For inhalation only

Don’t swallow the capsules. The capsules should only be used with the Neohaler inhaler that comes with the drug. Never place a capsule in the mouthpiece of the Neohaler inhaler.

Milk allergy

This drug contains lactose (milk sugar) and a small amount of milk proteins. Taking this drug may cause an allergic reaction if you have a severe milk protein allergy.

When to seek emergency help

Call your healthcare provider or seek medical care right away if your breathing problems get worse, you need to use your rescue medicine more often, or your rescue inhaler medicine doesn’t work as well to relieve your symptoms.

Drug features

This drug is a prescription drug. It’s available as inhalation powder in capsules. The capsules should only be used with the Neohaler inhaler that comes with the drug.

Arcapta is a brand-name drug. It isn’t available as a generic drug.

This drug may be used as part of a combination therapy. This means you may need to take it with other medications.

Why it's used

This drug is used to treat chronic obstructive pulmonary disease (COPD). This causes symptoms such as wheezing, cough, chest tightness, and shortness of breath.

How it works

This drug belongs to a class of drugs called long acting beta2-adrenergic agonists (LABA). A class of drugs is a group of medications that work in a similar way.

More Details

How it works

This drug belongs to a class of drugs called long acting beta2-adrenergic agonists (LABA).  A class of drugs is a group of medications that work in a similar way. They are often used to treat similar conditions. 

This drug helps the muscles around the airways in your lungs stay relaxed to prevent symptoms. These include wheezing, cough, chest tightness, and shortness of breath. This makes it easier for you to breathe.

Advertisement
SECTION 2 of 5

indacaterol Side Effects

Inhalation powder

More Common Side Effects

Some of the more common side effects of indacaterol include:

  • runny nose

  • cough

  • sore throat

  • headache

  • nausea

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious Side Effects

Call your doctor right away if you have serious side effects. Call 9-1-1 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • worsening symptoms of chronic obstructive pulmonary disease (COPD). Symptoms include:

    • wheezing
    • cough
    • chest tightness
    • shortness of breath
  • serious allergic reactions. Symptoms include:

    • skin rash
    • hives
    • swelling of your tongue, lips, and face
    • trouble breathing or swallowing 
  • sudden shortness of breath

  • fast or irregular heartbeat (palpitations)

  • increased blood pressure

  • heart problems. Symptoms include:

    • chest pain
    • muscle spasms
    • muscle weakness
    • abnormal heart rhythm
  • high blood sugar. Symptoms include:

    • frequent urination
    • intense thirst
    • blurred vision
    • headache
Pharmacist's Advice
Healthline Pharmacist Editorial Team

This drug doesn’t cause drowsiness.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
SECTION 3 of 5

indacaterol May Interact with Other Medications

Inhalation powder

Indacaterol can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Medications that might interact with this drug

Human immunodeficiency virus (HIV) drugs

Taking these drugs together may cause high levels of indacaterol in your body. This can cause more side effects.

These drugs include:

  • ritonavir

Antifungal drugs

Taking these drugs together may cause high levels of indacaterol in your body. This can cause more side effects.

These drugs include:

  • ketoconazole

Heart drugs

Taking these drugs together may cause high levels of indacaterol in your body. This can cause more side effects.

These drugs include:

  • verapamil

Antibiotics

Taking these drugs together may cause high levels of indacaterol in your body. This can cause more side effects.

These drugs include:

  • erythromycin

Asthma or chronic obstructive pulmonary disease drugs

These medications may increase the side effects on your heart that are seen with indacaterol. This may cause abnormal heart rhythms (arrhythmias).

These drugs include:

  • albuterol
  • arformoterol
  • formoterol  
  • formoterol/budesonide
  • formoterol/mometasone
  • indacaterol  
  • levalbuterol
  • metaproterenol
  • salmeterol
  • salmeterol/fluticasone  
  • terbutaline
  • vilanterol/fluticasone  
  • vilanterol/umeclidinium

Other drugs used to treat asthma may cause low blood potassium levels when taken with indacaterol. This may harm your heart.

These drugs include:

  • aminophylline
  • dyphylline
  • theophylline

Depression drugs

These medications may increase the side effects on your heart that are seen with indacaterol. This may cause abnormal heart rhythms (arrhythmias).

These drugs include:

  • monoamine oxidase inhibitors (MAOIs), such as:
    • isocarboxazid
    • phenelzine
    • selegiline
    • tranylcypromine
  • tricyclic antidepressants, such as:
    • amitriptyline
    • clomipramine
    • desipramine  
    • doxepin
    • imipramine
    • nortriptyline
    • protriptyline

High blood pressure and heart drugs

Drugs used for high blood pressure or other heart conditions can block the action of indacaterol. This can cause the vessels in your lungs to tighten or constrict. This may make it harder for you to breathe.

These drugs include:

  • beta blockers, such as:
    • acebutolol
    • atenolol
    • betaxolol
    • bisoprolol
    • esmolol
    • metoprolol
    • nadolol
    • nebivolol
    • penbutolol
    • pindolol
    • propranolol
    • sotalol
    • timolol

Water pills (diuretics)

Taking certain water pills with indacaterol may cause low potassium levels in your blood. This can be dangerous to your heart.

These drugs include:

  • loop diuretics, such as:
    • bumetanide
    • ethacrynate
    • furosemide
    • torsemide
  • thiazide diuretics, such as:
    • chlorothiazide
    • chlorthalidone
    • hydrochlorothiazide
    • indapamide
    • methyclothiazide
    • metolazone

Steroids

Taking certain steroids with indacaterol may cause low potassium levels in your blood. This can be dangerous to your heart.

These drugs include:

  • betamethasone
  • cortisone
  • dexamethasone
  • hydrocortisone
  • methylprednisolone
  • prednisone
  • triamcinolone

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
Drug warnings
People with heart problems

This drug may increase your blood pressure and heart rate, and cause abnormal heart rhythms (arrhythmias). Let your doctor know if you have any heart conditions before starting this drug.

seizures
People with seizures

This drug may increase your risk for seizures. Let your doctor know before starting this drug if you have a seizure disorder or epilepsy.

thyroid problems
People with thyroid problems

People with thyroid problems: This drug may increase thyroid activity. Ask your doctor whether this drug is safe for you if you have high thyroid levels.

diabetes
People with diabetes

This drug may increase your blood sugar levels. Tell your doctor if you have diabetes before you take this drug.

low potassium levels
People with low potassium levels (hypokalemia)

This drug may cause low blood potassium levels. If your potassium levels become too low, you may have heart effects, including abnormal heart rhythms (arrhythmias).

allergies
People with a milk allergy

This drug contains lactose (milk sugar) and a small amount of milk proteins. Taking this drug may cause an allergic reaction if you have a severe milk protein allergy.

pregnant women
Pregnant women

This drug is a category C pregnancy drug. That means two things:

  1. Research in animals has shown adverse effects to the fetus when the mother takes the drug.
  2. There haven’t been enough studies done in humans to be certain how the drug might affect the fetus.

Talk to your doctor if you’re pregnant or planning to become pregnant. This drug should only be used if the potential benefit justifies the potential risk to the fetus.

breastfeeding
Women who are breast-feeding

It isn’t known if this drug passes into breast milk. If it does, it may cause side effects in a child who is breast-fed.

Talk to your doctor if you breast-feed your baby. You may need to decide whether to stop breast-feeding or stop taking this medication.

for children
For children

This drug hasn’t been studied in children and shouldn’t be used in people younger than 18 years. This disease doesn’t normally occur in children.

call doctor
When to call the doctor

Call your healthcare provider or seek medical help right away if:

  • Your breathing problems worsen with this drug.
  • You need to use your rescue inhaler medication more often than usual.
  • Your rescue inhaler medication doesn’t work as well to relieve your symptoms.
allergies
Allergies

This drug can cause a severe allergic reaction. Symptoms can include:

  • skin rash
  • hives
  • swelling of your tongue, lips, and face
  • trouble breathing or swallowing 

Call 9-1-1 or go to the nearest emergency room if you develop these symptoms.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

SECTION 4 of 5

How to Take indacaterol (Dosage)

Inhalation powder

All possible dosages and forms may not be included here. Your doctor will tell you what dosage is right for you. Your dose, form, and how often you take it will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

What are you taking this medication for?

Chronic obstructive pulmonary disease (COPD)

Brand: Arcapta Neohaler

Form: Inhalation powder in capsules
Strengths: 75 mcg
Adult dosage (ages 18 years and older)

Inhale the contents of one 75 mcg indacaterol capsule using the Neohaler inhaler. Take this drug at the same time each day. Don’t swallow the capsules. If you swallow them, this drug won’t work the way it’s supposed to in your lungs.

Child dosage (ages 0–17 years)

This medication hasn’t been studied in children. It shouldn’t be used in people younger than 18 years. This disease doesn’t normally occur in children.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.
Pharmacist's Advice
Healthline Pharmacist Editorial Team

This drug comes with risks if you don’t take it as prescribed. 

If you stop taking the drug or don’t take it at all

Your symptoms will get worse. Your lung function will decline and you’ll have more trouble breathing. You may eventually need an oxygen tank.

If you miss doses or don’t take the drug on schedule

Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

If you take too much

If you take too much of this drug, you may have the following symptoms:

  • chest pain (angina)
  • high or low blood pressure
  • a fast or pounding heart rate
  • abnormal heart rhythms
  • nervousness
  • headache
  • tremor
  • dry mouth
  • muscle cramps
  • nausea
  • dizziness
  • tiredness
  • low potassium levels
  • too much acid in your body (metabolic acidosis)
  • trouble sleeping
  • heart attack

If you think you’ve taken too much of the drug, act right away. Call your doctor or local poison control center, or go to the nearest emergency room.

What to do if you miss a dose

If you miss a dose, take it as soon as you remember. Don’t take more than one dose in 24 hours.

How to tell if the drug is working

Your symptoms, such as shortness of breath, wheezing, and cough, will be better controlled. You’ll have fewer attacks or sudden symptoms of trouble breathing.

This drug is used for long-term treatment.

Important considerations for taking this drug

Don’t cut, crush, or puncture the capsule

It should only be used in the Neohaler inhaler and is only for oral inhalation.

Store this drug at room temperature

  • Keep it at 77°F (25°C). It may be stored very briefly from 59°F to 86°F (15°C to 30°C).
  • Protect this drug from moisture. Don’t store this medication in moist or damp areas, such as bathrooms.
  • Don’t remove the capsules from their foil package until just before you use them.
  • Keep the capsules out of the light.
  • Don’t store the capsules in the Neohaler inhaler.

A prescription for this medication is refillable

You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

  • Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
  • Don’t worry about airport x-ray machines. They can’t hurt your medication.
  • You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled box with you.
  • Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Self-management

Your doctor or pharmacist will show you how to use your inhaler properly.

This drug is supplied as a package that contains the capsules (in blister cards) and a Neohaler inhaler (consisting of a cap and a base). Don’t use the capsules with any other capsule inhaler. Don’t use the Neohaler inhaler to take any other capsule medication. You’ll breathe in (inhale) the medication in the capsules from the Neohaler inhaler. Don’t swallow the capsules. Follow the instructions that come with your inhaler or the directions given by your healthcare provider carefully.

Clinical monitoring

Your doctor will check your lung function to make sure your medication is working.

This monitoring may be done using this test:

  • Pulmonary function tests (PFTs): Your doctor will do PFTs to measure how well your lungs are working. During this test, you'll blow into a large tube connected to a machine called a spirometer. The spirometer measures how much air your lungs can hold and how fast you can blow the air out of your lungs.

You and your doctor should monitor certain health issues. This can help make sure you stay safe while you take this drug. These issues include:

  • Blood potassium levels: This drug may cause low potassium levels in some people. Low potassium levels may lead to heart problems.
  • Blood sugar levels: This drug may increase your blood sugar (hyperglycemia). If you have diabetes, you’ll need to monitor your blood sugar closely.

Insurance

Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription.

Are there any alternatives?

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other options that may work for you.

SECTION 5 of 5

How Much Does indacaterol Cost?

Inhalation powder

We've partnered with GoodRx so you can compare prices, find discounts and save up to 80% on your next prescription. Check out the low coupon prices below — no insurance required.

Compare prices and save up to 80% on your next refill!

Lowest price for indacaterol

Membership warehouse $220.65
Kroger Pharmacy $221.39
Target (CVS) $226.87
These prices represent the lowest priced national pharmacies for indacaterol on GoodRx. They may be lower than your insurance.

Enter your zip code to find the best deal near you.

These prices represent the lowest priced national pharmacies for indacaterol on GoodRx. They may be lower than your insurance.

Content developed in collaboration with University of Illinois-Chicago, Drug Information Group

Medically reviewed by Creighton University, Center for Drug Information and Evidence-Based Practice on October 27, 2015

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
Advertisement
Advertisement
Advertisement