Generic Name: flurbiprofen, Oral tablet

Generic Name:

flurbiprofen, Oral tablet

Ansaid

All Brands

  • Ansaid
SECTION 1 of 5

Highlights for flurbiprofen

Oral tablet
1

Flurbiprofen is an oral medication used to treat symptoms of osteoarthritis and rheumatoid arthritis, such as pain.

2

Common side effects include stomach pain, diarrhea, gas, constipation, heartburn, and dizziness.

3

Take your doses of flurbiprofen with a glass of water and food to prevent upset stomach. Try not to lie down for at least 10 minutes after you take your dose. Lying down might increase your chance of an upset stomach.

4

Before starting this drug, tell your doctor if you smoke cigarettes or have more than 3 alcoholic drinks per day. These behaviors can increase your risk of stomach problems, including ulcers and bleeding.

5

Take this medication with caution if you have a history of heart disease, risk factors for heart disease, such as high blood pressure, or have a history of stomach bleeding.

IMPORTANT INFORMATION

FDA Warning

This drug has a Black Box Warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients to potentially dangerous effects.

Heart risks. Use this medication with caution if you have heart disease or if you have risks for heart disease. Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID). NSAIDs can increase your risk of blood clot, heart attack, and stroke, which may lead to death.

You should not take this medication to treat pain after coronary artery bypass graft surgery. It can increase your risk of having a heart attack or stroke.

Stomach problems. Flurbiprofen can increase your risk of stomach bleeding or holes in the lining of your stomach or intestines (peptic ulcers). These conditions can be fatal. They may occur at any time and may not have signs or symptoms. Seniors are at greater risk. 

May cause allergic reaction

This medication can cause a severe allergic reaction. Symptoms may include:

  • hives
  • trouble breathing
  • swelling of your throat or tongue
  • rash
  • chest pain

Don’t take flurbiprofen if you’ve experienced any of these allergic-type reactions or asthma after taking aspirin or other NSAIDs.

May cause high blood pressure

Flurbiprofen can lead to increased blood pressure in people who don’t already have high blood pressure.

May cause kidney damage

Using this medication long term can cause kidney damage. Seniors are at increased risk.

Drug Features:

Flurbiprofen is a prescription medication. It’s available as an oral tablet.

Flurbiprofen is available in its generic form. Generic drugs usually cost less. In some cases they may not be available in every strength or form as the brand. Talk to your healthcare provider to see if the generic will work for you.

Why It's Used

Flurbiprofen is used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.

How It Works

Flurbiprofen works to reduce inflammation and pain. It belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).

SECTION 2 of 5

flurbiprofen Side Effects

Oral tablet

Most Common Side Effects

The most common side effects that occur with flurbiprofen include:

  • constipation

  • diarrhea

  • dizziness

  • heartburn

  • upset stomach

Serious Side Effects

If you experience any of these serious side effects, call your doctor right away. If your symptoms are potentially life threatening or if you think you’re experiencing a medical emergency, call 9-1-1.
  • chest pain or heart attack. Other symptoms of heart attack may include:

    • shortness of breath
    • sweating
    • fatigue
    • heartburn
    • arm pain
  • stroke. Symptoms may include:

    • weakness in one part or side of your body
    • slurred speech
  • high blood pressure

  • swelling in your arms and legs, hands and feet, or unusual weight gain

  • bleeding and ulcers in your stomach and intestines. Symptoms may include:

    • blood in your urine or vomit
    • black or bloody stools
    • nausea or vomiting
    • severe stomach pain
  • skin reactions, including rash or blisters

  • allergic reactions. Symptoms may include:

    • itching
    • swelling of your face or throat
    • skin rash
    • hives
  • liver problems. Symptoms may include:

    • yellowing of your skin or the whites of your eyes
    • feeling unusually weak or tired
  • asthma attacks. Symptoms may include:

    • trouble breathing
    • wheezing
Pharmacist's Advice
Healthline Pharmacist Editorial Team

Flurbiprofen does not cause drowsiness.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
SECTION 3 of 5

flurbiprofen May Interact with Other Medications

Oral tablet

Flurbiprofen can interact with other medications, herbs, or vitamins you might be taking. That’s why your doctor should manage all of your medications carefully. If you’re curious about how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Note: You can reduce your chances of drug interactions by having all of your prescriptions filled at the same pharmacy. That way, a pharmacist can check for possible drug interactions.

Alcohol Interaction

Drinking alcohol while taking flurbiprofen can irritate your stomach. This can lead to ulcers or bleeding from your stomach or intestines, which can be fatal.

Medications That Might Interact with This Drug

Disease-modifying antirheumatic drug
  • methotrexate

Combining these drugs can increase the levels of methotrexate in your body, which can be toxic.

Anticoagulant, blood thinner
  • warfarin

Combining these drugs increases your risk of stomach bleeding.

Bipolar disorder medication
  • lithium

Flurbiprofen may cause amounts of lithium in your blood to increase to toxic levels. Symptoms of lithium toxicity may include tremors, excessive thirst, or confusion.

Blood pressure drugs

These include:

  • angiotensin-converting enzyme (ACE) inhibitors
  • beta blockers, such as propranolol

Flurbiprofen may reduce the blood pressure-lowering effects of these drugs.

Diuretics

Flurbiprofen can decrease the effect of some diuretics, including:

  • hydrochlorothiazide
  • furosemide

Nonsteroidal anti-inflammatory drugs (NSAIDs)

Examples are:

  • aspirin
  • ibuprofen
  • naproxen
  • etodolac
  • diclofenac
  • fenoprofen
  • ketoprofen
  • tolmetin
  • indomethacin
  • meloxicam (excluding COX2 inhibitors)

Flurbiprofen is a NSAID. Combining it with other NSAIDs may increase your risk for side effects, such as stomach bleeding or ulcers.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

People with heart disease

If you have heart disease or are at risk of heart disease, you shouldn’t take flurbiprofen. It may increase your risk of blood clots, heart attack, or stroke.

People with high blood pressure

Flurbiprofen can cause high blood pressure or make high blood pressure worse. Your doctor may monitor you closely if you have high blood pressure or congestive heart failure while you take flurbiprofen.

People with stomach problems

This medication increases your risk of ulcers and stomach bleeding if you have a history of these conditions.

People with kidney disease

Your body may not be able to remove flurbiprofen as well as it should. This can cause the medication to build up in your body, which could cause more side effects.

Pregnant women

Flurbiprofen falls into one of two pregnancy categories, depending on how far along you are in your pregnancy.

After week 30, flurbiprofen is a category D pregnancy drug. That means:

  1. Studies show a risk of adverse effects to the fetus when the mother takes the drug.
  2. This drug should only be used during pregnancy in serious cases where it's needed to treat a dangerous condition in the mother.

You shouldn’t take this medication if you’re 30 weeks pregnant or beyond.

Up until week 30, flurbiprofen is a category C pregnancy drug. That means:

  1. Research in animals has shown adverse effects to the fetus when the mother takes the drug.
  2. There haven’t been enough studies done in humans to be certain how the drug might affect the fetus.

Tell your doctor if you’re pregnant or plan to become pregnant.

Women who are nursing

Flurbiprofen has been shown to pass through breast milk. This could cause side effects in a child who breastfeeds. Tell your doctor if you’re breastfeeding. You may need to decide whether to stop breastfeeding or stop using flurbiprofen.

For Seniors

People aged 65 years and older are at risk of increased stomach problems and kidney failure. If you’re older than 65 years, your doctor may adjust your dose.

For Children

The safety and effectiveness of flurbiprofen haven’t been established in people under the age of 18 years.

Allergies

Flurbiprofen can cause a severe allergic reaction. Symptoms may include:

  • trouble breathing
  • swelling of your throat or tongue
  • hives

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal.

SECTION 4 of 5

How to Take flurbiprofen (Dosage)

Oral tablet

All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

What Are You Taking This Medication For?

Osteoarthritis
Form: Oral Tablet
Strengths: 50 mg and 100 mg
Adult Dosage (ages 18–64 years)

200–300 mg per day divided into 2 to 4 evenly spaced doses. Don’t take more than 100 mg per dose.

Child Dosage (ages 0–17 years)

Dosage for people younger than 18 years hasn’t been established.

Senior Dosage (ages 65 years and older)

Never take more than 100 mg in a single dose. The maximum dose of flurbiprofen is 300 mg per day.

Special Considerations

Kidney Disease: Your dose of flurbiprofen may need to be lowered if you have kidney disease.

Rheumatoid arthritis
Form: Oral Tablet
Strengths: 50 mg and 100 mg
Adult Dosage (ages 18–64 years)

200–300 mg per day divided into 2 to 4 evenly spaced doses. Don’t take more than 100 mg per dose.

Child Dosage (ages 0–17 years)

Dosage for people younger than 18 years hasn’t been established.

Senior Dosage (ages 65 years and older)

Never take more than 100 mg in a single dose. The maximum dose of flurbiprofen is 300 mg per day.

Special Considerations

Kidney Disease: Your dose of flurbiprofen may need to be lowered if you have kidney disease.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.
Pharmacist's Advice
Healthline Pharmacist Editorial Team

Flurbiprofen comes with risks if you don’t take it as prescribed by your doctor.

If You Stop or Miss Doses

If you stop taking flurbiprofen, miss doses, or don’t take it on schedule, you may experience more pain caused by your condition.

What to Do If You Miss a Dose

If you miss a dose, take it as soon as you can. However, if it’s almost time for your next dose, wait and take a single dose at the usual time.

Never try to catch up by taking two doses at once. This could result in toxic side effects.

How to Tell If the Drug Is Workinge

You may be able to tell this medication is working if you notice a decrease in pain and swelling. Tell your doctor if your symptoms don’t get better.

Flurbiprofen is a long-term treatment when used for arthritis.

Take flurbiprofen with food

This can help to lower your risk of getting an upset stomach or an ulcer.

Take your dose at regular intervals

For example: If your doctor prescribes flurbiprofen 3 times a day, take each dose 8 hours apart.

Store at room temperature: 68–77°F (20–25°C)

Keep the container tightly closed. Throw away any unused medicine after the expiration date.

Note: Keep your medications away from areas where they could get wet, such as bathrooms. Store them away from moisture and damp locations.

Travel

When traveling with your medication:

  • Always carry it with you or in your carry-on bag.
  • Don’t worry about airport X-ray machines. They can’t hurt this medication.
  • You may need to show your pharmacy’s preprinted label to identify the medication. Keep the original prescription-labeled box with you when traveling.

Clinical Monitoring

If you’re taking flurbiprofen long term, your doctor may do a blood test to check for signs of bleeding.

They may monitor you for signs of stomach or intestinal bleeding or ulcers.

Your doctor might also monitor your blood pressure.

Are There Any Alternatives?

There are other drugs available to treat your condition. Some may be more suitable for you than others. Talk to your doctor about possible alternatives.

What does the pill look like?

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SECTION 5 of 5

How Much Does flurbiprofen Cost?

Oral tablet
We've partnered with GoodRX so you can compare prices and save money on your next prescription. Check out the lowest cash prices below and enter your zip code to find the best deal near you.

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Lowest price for flurbiprofen

Walgreens $15.00
Target $18.35
Walmart $18.41
These represent the lowest cash prices for flurbiprofen and may be lower than your insurance.

Find the lowest prices of flurbiprofen near you

These represent the lowest cash prices for flurbiprofen and may be lower than your insurance.

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Content developed in collaboration with University of Illinois-Chicago, Drug Information Group

Medically reviewed by Creighton University, Center for Drug Information and Evidence-Based Practice on May 6, 2015

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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