Highlights for everolimus
everolimus Side Effects
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- breathing problems
- chest pain
- dark urine
- fever or chills, sore throat
- increased hunger or thirst
- increased urination
- nausea, vomiting
- stomach pain
- swelling of ankles, feet, hands
- trouble passing urine or change in the amount of urine
- unusual bleeding or bruising
- unusually weak or tired
Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):
- dry mouth or mouth sores
- nausea, vomiting
everolimus May Interact with Other Medications
This medicine may interact with the following medications:
- antiviral medicines for HIV or AIDS
- certain medicines for cholesterol like simvastatin
- grapefruit juice
- live vaccines
How to Use everolimus
Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. You can take this medicine with or without food, but always take Zortress the same way. Do not cut, crush, or chew this medicine. Do not take with grapefruit juice. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
They need to know if you have any of these conditions:
- heart disease
- high cholesterol
- immune system problems
- infection (especially a virus infection such as chickenpox, cold sores, or herpes)
- kidney disease
- liver disease
- low blood counts, like low white cell, platelet, or red cell counts
- rare hereditary problems of galactose intolerance, the Lapp lactase deficiency, or glucose-galactose malabsorption
- an unusual or allergic reaction to everolimus, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop. Visit your doctor or health care professional for regular check-ups. You may need regular tests to monitor possible side effects of the drug.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
Do not become pregnant while taking this medicine or for 8 weeks after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 2 weeks after stopping it.
This medicine has caused ovarian failure in some women. This medicine may interfere with the ability to have a child. You should talk with your doctor or health care professional if you are concerned about your fertility.
This medicine has caused reduced sperm counts in some men. This may interfere with the ability to father a child. You should talk to your doctor or health care professional if you are concerned about your fertility.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
If you have had a kidney transplant, immediately tell your doctor if your incision site is red, warm, or painful. Also, tell your doctor if your incision site opens up or swells or if contains blood, fluid, or pus.
Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
Last Updated: February 9, 2016