Generic Name: elvitegravir, Oral tablet

VITEKTA

All Brands

  • VITEKTA
SECTION 1 of 5

Highlights for elvitegravir

Oral tablet
1

Vitekta is an oral tablet used to treat human immunodeficiency virus (HIV) infection. It’s always taken with a protease inhibitor, ritonavir, and another antiretroviral drug.

2

Vitekta is taken once per day with food.

3

The dose is either 85 mg or 150 mg per day, depending on which protease inhibitor you’re taking.

4

Most side effects are mild. They include diarrhea, nausea, and headache.

5

There is a small risk of severe depression while taking this drug. Your risk is higher if you’ve had depression or psychiatric illness in the past.

IMPORTANT INFORMATION

Cobicistat (Tybost) warning

Don’t take Vitekta with protease inhibitors and cobicistat (Tybost). This could lead to low levels of your human immunodeficiency virus (HIV) medications, which could cause them not to work. 

Do not use with other elvitegravir drugs

Don’t use Vitekta with other drugs that contain elvitegravir, including Stribild.

May cause immune reconstitution syndrome

Your recovering immune system may result in your body recognizing previous infections you’ve had. Past infections that may require treatment include fungal infections, pneumonia, or tuberculosis. Watch for returning symptoms of past infections.

Drug Features

Vitekta is a prescription drug. It is available in these forms: oral tablet.

Vitekta is used as part of a combination therapy. That means you’ll need to take it in combination with other drugs.

Why It's Used

Vitekta is used in combination with other antiretroviral drugs to treat human immunodeficiency virus (HIV) infection in adults who have been previously treated for HIV infection. It must be used in combination with a protease inhibitor, ritonavir, and another antiretroviral drug.

How It Works

Vitekta works to stop human immunodeficiency virus (HIV) from copying itself and spreading in your body.

HIV uses an enzyme called integrase to merge with DNA in your healthy cells and spread through your body. Vitekta blocks this enzyme action, which prevents HIV from replicating and spreading.

SECTION 2 of 5

elvitegravir Side Effects

Oral tablet

Most Common Side Effects

This drug has very few reported side effects. The most common side effects that occur with Vitekta include:

  • diarrhea

  • nausea

  • headache

  • stomach pain

  • vomiting

  • fatigue

  • rash

Serious Side Effects

If you experience any of these serious side effects, call your doctor right away. If your symptoms are potentially life threatening, or if you think you’re experiencing a medical emergency, call 9-1-1.

  • severe depression and suicidal thoughts. This risk is small but more likely if you’ve had depression or other psychiatric illness. Call your doctor right away or call 9-1-1 if you feel very depressed or have thoughts of harming yourself.
  • immune reconstitution syndrome. Your recovering immune system may result in your body recognizing previous infections you’ve had. Past infections that may require treatment include fungal infections, pneumonia, or tuberculosis. Watch for returning symptoms of past infections.
Pharmacist's Advice
Healthline Pharmacist Editorial Team

Vitekta does not cause drowsiness.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
SECTION 3 of 5

elvitegravir May Interact with Other Medications

Oral tablet

Vitekta can interact with other medications, herbs, or vitamins you might be taking. That’s why your doctor should manage all of your medications carefully. If you’re curious about how this drug might interact with something else you’re taking, talk to your doctor or pharmacist. 

Note: You can reduce your chances of drug interactions by having all of your prescriptions filled at the same pharmacy. That way, a pharmacist can check for possible drug interactions.

Medications That Might Interact with This Drug

Human immunodeficiency virus (HIV) drugs
  • indinavir (Crixivan)
  • nelfinavir (Viracept)
  • saquinavir (Invirase)  
  • cobicistat (Tybost) 
  • atazanavir (Reyataz) Note: This drug is used with Vitekta to improve the effect of both drugs.
  • didanosine (Videx EC)
  • efavirenz (Sustiva)
  • Lopinavir/ritonavir (Kaletra) Note: These drugs are used with Vitekta to increase the effectiveness of the HIV treatment regimen.
  • nevirapine (Viramune)

Acid-reducing drugs (antacids)

Don’t take these over-the-counter medications within 2 hours of taking Vitekta:

  • magnesium hydroxide
  • calcium
  • aluminum hydroxide

Antibiotics and other drugs to treat infections
  • rifabutin (Mycobutin)
  • rifampin (Rifadin)
  • rifapentine (Priftin)

Antifungal drug
  • ketoconazole

Epilepsy drugs
  • carbamazepine     
  • oxcarbazepine (Oxtellar XR, Trileptal)
  • phenobarbital
  • phenytoin (Dilantin)

Hepatitis drugs
  • boceprevir (Victrelis) for hepatitis C
  • telaprevir (Incivek) for hepatitis C

Herbal supplement
  • St. John’s wort

Oral contraceptives/hormones
  • ethinyl estradiol and other estrogens
  • norgestimate

Pulmonary arterial hypertension drug
  • bosentan (Tracleer)

Steroid
  • dexamethasone (Decadron)

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

People with liver disease

If you have severe liver disease, your doctor may not want to give you Vitekta because it’s mostly processed in your liver. There haven’t been enough studies done in people with severe liver disease to know how the drug should be dosed or if it’s safe to use. Talk to you doctor before taking this drug.

Pregnant women

Vitekta is a pregnancy category B drug. That means two things:

  1. Studies of the drug in pregnant animals have not shown risk to the fetus.
  2. There aren’t enough studies done in pregnant women to show if the drug poses a risk to the fetus.

Vitekta should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Women who are nursing

You shouldn’t breastfeed while taking this drug.

According to the U.S. Department of Health and Human Services, you shouldn’t breastfeed your infant if you have human immunodeficiency virus (HIV) infection. There’s a risk of passing HIV to your baby. Additionally, animal studies showed that Vitekta passes through the breast milk of animals. 

For Seniors

If you’re older than 65 years, you may have reduced kidney and liver function. Your doctor may monitor you more closely with blood tests while you take this drug.

When to call the doctor

Call your doctor if you experience:

  • fever
  • weakness
  • chills
  • night sweats
  • sore throat
  • joint pain

These symptoms may be a sign the drug isn’t working, and you may need a different treatment. 

Allergies

The most common allergic reaction to Vitekta is a mild rash. See a doctor or go to an emergency room right away if you experience a severe rash, itching, hives, or breathing problems after taking this drug.

SECTION 4 of 5

How to Take elvitegravir (Dosage)

Oral tablet

All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

This medication is always taken in combination with a protease inhibitor and ritonavir.

What Are You Taking This Medication For?

Human immunodeficiency virus (HIV) infection

Brand: Vitekta

Form: Oral Tablet
Strength: 85 mg and 150 mg
Adult Dosage (ages 18-64 years)

The dose is 85 mg or 150 mg taken once per day with food. Your dose will depend on which protease inhibitor you’re taking.

Child Dosage (ages 0-17 years)

Dosage hasn’t been established for people 17 years old or younger.

Senior Dosage (ages 65 years and older)

If you’re older than 65 years, you may have reduced kidney and liver function. Your doctor may adjust your dose accordingly.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.
Pharmacist's Advice
Healthline Pharmacist Editorial Team

Keeping human immunodeficiency virus (HIV) infection under control requires lifelong treatment. There can be serious health consequences if you don’t take this drug exactly how your doctor tells you.

If You Don’t Take It at All

Your HIV infection may eventually reduce your immunity to a point that your body can’t defend itself against many types of infections. You may not be able to defend against infections that are commonly cured in people who don’t have HIV infection.

If You Stop or Miss Doses

If you stop taking this medication, miss doses, or don’t take it on schedule, the amount of medication in your body fluctuates. This can allow the HIV in your body to become resistant to the drug, which means the drug stops working.

If You Don’t Take It on Schedule

Taking your drug at the same time every day keeps a constant amount of the drug in your body. This helps make the drug as effective as possible at keeping the virus under control.

If You Don’t Take It in Combination with other Drugs

If you don’t take Vitekta in combination with a protease inhibitor, ritonavir, and another antiretroviral drug, your HIV infection might not be controlled.

What to Do if You Miss a Dose

In most cases, if you forget to take your dose, take it as soon as you remember. However, if it's just a few hours until your next dose, take your dose at the usual time.

Take just one dose at a time. Never try to catch up by taking two doses at once. This could result in toxic side effects.

How Can I Tell if the Drug Is Working?

To see how well your treatment is working, your doctor will check your:

  • virus count. A virus count measures the number of copies of HIV in your body. A decreased virus count is a sign that your treatment is working.
  • CD4 count. A CD4 count measures the number of CD4 cells in your body. CD4 cells are white blood cells that fight infection. An increased CD4 count is a sign that your treatment is working.

Vitekta is a long-term drug treatment.

Take Vitekta at the same time every day for the best possible effect

Ask your doctor or pharmacist to help you schedule the dosing of your medications.

Store Vitekta in temperatures from 59–86°F (15–30°C)

Keep the drug in its original container. 

Note: Be careful of moist environments, including bathrooms. To keep drugs away from moisture, store them somewhere other than your bathroom and any other damp location.

Clinical Monitoring

To see how well your treatment is working, your doctor will check your:

  • virus count. A virus count measures the number of copies of human immunodeficiency virus (HIV) in your body. A decreased virus count is a sign that your treatment is working.
  • CD4 cell count. A CD4 cell count measures the number of CD4 cells in your body. CD4 cells are white blood cells that fight infection. An increased CD4 count is a sign that your HIV treatment is working.

Your doctor may also check your liver and kidney function before and during treatment.

Not every pharmacy stocks this drug, so call ahead

If you only need a few tablets, you should call and ask if your pharmacy dispenses only a small number of tablets. Some pharmacies can't dispense only part of a bottle.

This drug is often available from specialty pharmacies through your insurance plan. These pharmacies operate like mail order pharmacies and ship the drug to you.

In larger cities, there will often be human immunodeficiency virus (HIV) pharmacies where you can have your prescriptions filled. Ask your doctor if there's an HIV pharmacy in your area.

Insurance

Many insurance companies will require a prior authorization before they approve the prescription and pay for Vitekta. Your doctor may need to do paperwork for you, which could take a week or two.

Are There Any Alternatives?

There are many drugs and combinations that can treat human immunodeficiency virus (HIV). Some may be more suitable for you than others. Talk to your doctor about possible alternatives.

SECTION 5 of 5

How Much Does elvitegravir Cost?

Oral tablet
We've partnered with GoodRX so you can compare prices and save money on your next prescription. Check out the lowest cash prices below and enter your zip code to find the best deal near you.

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Lowest price for elvitegravir

Membership warehouse $1,146.08
Publix $1,150.17
Kroger Pharmacy $1,150.58
These represent the lowest cash prices for elvitegravir and may be lower than your insurance.

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These represent the lowest cash prices for elvitegravir and may be lower than your insurance.

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Content developed in collaboration with Susan J. Bliss, RPh, MBA

Medically reviewed by Creighton University, Center for Drug Information and Evidence-Based Practice on April 29, 2015

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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