Generic Name: donepezil, Oral tablet

Generic Name:

donepezil, Oral tablet

Aricept Aricept

All Brands

  • Aricept
SECTION 1 of 5

Highlights for donepezil

Oral tablet
DONEPEZIL (doe NEP e zil) is used to treat mild to moderate dementia caused by Alzheimer's disease.
This drug also comes in other forms, including Oral SolutionOrally disintegrating solid
3 4 5
Talk to your healthcare provider if you have any of these conditions.
Know what to watch for and get tips for reducing your risks while taking this drug.
SECTION 2 of 5

donepezil Side Effects

Oral tablet

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • changes in vision
  • feeling faint or lightheaded, falls
  • problems with balance
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • slow heartbeat, or palpitations
  • stomach pain
  • unusual bleeding or bruising, red or purple spots on the skin
  • vomiting
  • weight loss

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea, especially when starting treatment
  • headache
  • indigestion or heartburn
  • loss of appetite
  • muscle cramps
  • nausea
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donepezil May Interact with Other Medications

Oral tablet

Do not take this medicine with any of the following medications:

  • certain medicines for fungal infections like itraconazole, fluconazole, posaconazole, and voriconazole
  • cisapride
  • dextromethorphan; quinidine
  • dofetilide
  • dronedarone
  • pimozide
  • quinidine
  • thioridazine
  • ziprasidone

This medicine may also interact with the following medications:

  • antihistamines for allergy, cough and cold
  • atropine
  • bethanechol
  • carbamazepine
  • certain medicines for bladder problems like oxybutynin, tolterodine
  • certain medicines for Parkinson's disease like benztropine, trihexyphenidyl
  • certain medicines for stomach problems like dicyclomine, hyoscyamine
  • certain medicines for travel sickness like scopolamine
  • dexamethasone
  • ipratropium
  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
  • other medicines for Alzheimer's disease
  • other medicines that prolong the QT interval (cause an abnormal heart rhythm)
  • phenobarbital
  • phenytoin
  • rifampin, rifabutin or rifapentine
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
SECTION 4 of 5

How to Use donepezil

Oral tablet

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You may take this medicine with or without food. Take this medicine at regular intervals. This medicine is usually taken before bedtime. Do not take it more often than directed. Continue to take your medicine even if you feel better. Do not stop taking except on your doctor's advice.

If you are taking the 23 mg donepezil tablet, swallow it whole; do not cut, crush, or chew it.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • asthma or other lung disease
  • difficulty passing urine
  • head injury
  • heart disease
  • history of irregular heartbeat
  • liver disease
  • seizures (convulsions)
  • stomach or intestinal disease, ulcers or stomach bleeding
  • an unusual or allergic reaction to donepezil, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding
What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose, do not take double or extra doses.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Check with your doctor or health care professional if your symptoms do not get better or if they get worse.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you.

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

What does the pill look like?

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SECTION 5 of 5

How Much Does donepezil Cost?

Oral tablet

We've partnered with GoodRx so you can compare prices, find discounts and save up to 80% on your next prescription. Check out the low coupon prices below — no insurance required.

Compare prices and save up to 80% on your next refill!

Lowest price for donepezil

Walmart $8.20
Sams Club $8.20
Kroger Pharmacy $10.20
These prices represent the lowest priced national pharmacies for donepezil on GoodRx. They may be lower than your insurance.

Enter your zip code to find the best deal near you.

These prices represent the lowest priced national pharmacies for donepezil on GoodRx. They may be lower than your insurance.

Last Updated: July 30, 2015

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