Highlights for dolutegravir
dolutegravir Side Effects
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- breathing problems
- muscle or joint pain
- redness, blistering, peeling or loosening of the skin, including inside the mouth
- unusually weak or tired
- weight gain around waist, back, or thinning of face, arms, legs
Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):
- nausea, vomiting
- stomach pain
- trouble sleeping
dolutegravir May Interact with Other Medications
Do not take this medicine with any of the following medications:
This medicine may also interact with the following medications:
- antiviral medicines for HIV or AIDS like efavirenz, etravirine, nevirapine, fosamprenavir/ritonavir, tipranavir/ritonavir
- buffered medicines, like buffered aspirin
- calcium supplements
- certain antacids
- certain laxatives
- certain medicines for seizures like carbamazepine, oxcarbazepine, phenytoin, phenobarbital
- iron supplements
- St. John's Wort; Hypericum perforatum
How to Use dolutegravir
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your anti-HIV therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years for selected conditions, precautions do apply.
Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.
They need to know if you have any of these conditions:
- liver disease
- an unusual or allergic reaction to dolutegravir, other medicines, lactose, foods, dyes, or preservatives
- pregnant or trying to get pregnant
If you miss a dose, take it as soon as you can. If your next dose is to be taken in less than 4 hours, then do not take the missed dose. Take the next dose at your regular time. Do not take double or extra doses.
Visit your doctor or health care professional for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.
HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.
Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.
Last Updated: August 15, 2013