Generic Name: diltiazem, Oral tablet

Cardizem,Cardizem LA,Matzim LA,Tiamate

All Brands

  • Cardizem
  • Cardizem LA
  • Matzim LA
  • Tiamate
SECTION 1 of 4

Highlights for diltiazem

Oral tablet
1
DILTIAZEM (dil TYE a zem) is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do. This medicine is used to treat high blood pressure and chest pain caused by angina.
2
This drug also comes in other forms, including Oral capsuleParenteral Solution
3 4 5
Talk to your healthcare provider if you have any of these conditions.
6
Know what to watch for and get tips for reducing your risks while taking this drug.
SECTION 2 of 4

diltiazem Side Effects

Oral tablet

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • confusion, mental depression
  • feeling faint or lightheaded, falls
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • slow, irregular heartbeat
  • swelling of the feet and ankles
  • unusual bleeding or bruising, pinpoint red spots on the skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation or diarrhea
  • difficulty sleeping
  • facial flushing
  • headache
  • nausea, vomiting
  • sexual dysfunction
  • weak or tired
SECTION 3 of 4

diltiazem May Interact with Other Medications

Oral tablet

Do not take this medicine with any of the following medications:

  • cisapride
  • hawthorn
  • pimozide
  • ranolazine
  • red yeast rice

This medicine may also interact with the following medications:

  • buspirone
  • carbamazepine
  • cimetidine
  • cyclosporine
  • digoxin
  • local anesthetics or general anesthetics
  • lovastatin
  • medicines for anxiety or difficulty sleeping like midazolam and triazolam
  • medicines for high blood pressure or heart problems
  • quinidine
  • rifampin, rifabutin, or rifapentine
SECTION 4 of 4

How to Use diltiazem

Oral tablet

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Swallow whole, do not crush or chew. Ask your doctor or pharmacist if your should take this medicine with food. Take your doses at regular intervals. Do not take your medicine more often then directed. Do not stop taking except on the advice of your doctor or health care professional. Ask your doctor or health care professional how to gradually reduce the dose.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • heart problems, low blood pressure, irregular heartbeat
  • liver disease
  • previous heart attack
  • an unusual or allergic reaction to diltiazem, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding
What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What should I watch for while using this medicine?

Check your blood pressure and pulse rate regularly. Ask your doctor or health care professional what your blood pressure and pulse rate should be and when you should contact him or her.

You may feel dizzy or lightheaded. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can make you more dizzy or increase flushing and rapid heartbeats. Avoid alcoholic drinks.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from humidity. Throw away any unused medicine after the expiration date.

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Last Updated: January 9, 2009

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