Generic Name:

cefotaxime, Injectable Solution

All Brands

  • Claforan
SECTION 1 of 4

Highlights for cefotaxime

Injectable Solution
CEFOTAXIME (sef oh TAKS eem) is a cephalosporin antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.
2 3 4
Talk to your healthcare provider if you have any of these conditions.
Know what to watch for and get tips for reducing your risks while taking this drug.
SECTION 2 of 4

cefotaxime Side Effects

Injectable Solution

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • dark urine
  • difficulty breathing, wheezing
  • irregular heartbeat
  • feeling faint
  • fever
  • pain or difficulty passing urine
  • pain, swelling and irritation at the injection site
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • seizures
  • unusual bleeding, bruising
  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea
  • headache
  • nausea, vomiting
  • vaginal itch, irritation
SECTION 3 of 4

cefotaxime May Interact with Other Medications

Injectable Solution

This medicine may interact with the following medications:

  • birth control pills
  • certain medicines for infection like amikacin, gentamicin, tobramycin
  • diuretics
  • NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen
  • probenecid
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
SECTION 4 of 4

How to Use cefotaxime

Injectable Solution

This medicine is injected into a muscle, or infused through a vein. It is usually given by a health care professional in a hospital or clinic setting.

If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • bleeding problems
  • kidney disease
  • stomach, intestinal problems like colitis
  • an unusual or allergic reaction to cefotaxime, cephalosporin or penicillin antibiotics, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding
What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not begin to improve or if you get new symptoms. Your doctor will monitor your condition and blood work as needed.

Do not treat diarrhea with over-the-counter products. Contact your doctor if you have diarrhea that lasts more than 2 days or if the diarrhea is severe and watery.

This medicine can interfere with some urine glucose tests. If you use such tests, talk with your health care professional.

If you are being treated for a sexually transmitted disease, avoid sexual contact until you have finished your treatment. Your sexual partner may also need treatment.

Where should I keep my medicine?

Keep out of the reach of children.

You will be instructed on how to store this medicine. Throw away any unused medicine after the expiration date on the label.

Last Updated: April 30, 2015

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