Bepotastine | Side Effects, Dosage, Uses & More
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Generic Name:

bepotastine, Ophthalmic Solution

All Brands

  • Bepreve
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Highlights for bepotastine

Ophthalmic Solution
1

Bepotastine eye drops are used to treat allergic conjunctivitis. This is an allergic condition that causes itching in the eyes. It can also cause eye redness, watering, swelling, or irritation.

2

Bepotastine is available as the brand-name drug Bepreve. It’s not available in a generic form.

3

Bepotastine eye drops are put (instilled) into the affected eye(s) twice each day.

4

The most common side effect of this drug is a mild bitter or metallic taste in the mouth after putting the eye drops into the eye(s). Less common side effects include eye irritation, headache, or swelling of the nose and throat.

5

Don’t use bepotastine to treat contact lens-related irritation. A preservative in the solution, benzalkonium chloride, may be absorbed by your contact lenses. If your eyes get red and itchy while wearing contact lenses, take out the lenses. Then put bepotastine eye drops into your eyes. Wait at least 10 minutes before putting the lenses back in.

IMPORTANT INFORMATION

For eye use only

Use the eye drops only in your eyes. This medication should not be put into your ears or your mouth.

Proper use

To prevent getting germs into your eyes, don’t touch your eyelids or other areas around your eyes with the tip of the dropper. Keep the bottle tightly closed when you’re finished putting in the eye drops.

Contact lenses

Don’t use this drug to treat contact lens-related irritation. A preservative in the solution, benzalkonium chloride, may be absorbed by your contact lenses. If your eyes get red and itchy while wearing contact lenses, take out the lenses. Then put the eye drops into your eyes. Wait at least 10 minutes before putting the lenses back in.

Drug features

This drug is a prescription drug. It’s only available as the brand-name drug Bepreve. It’s not available in a generic form.

This drug comes in the form of drops that are put (instilled) into your eyes. This drug may be used as part of a combination therapy. This means you may need to take it with other medications.

Why it's used

This drug is used to treat allergic conjunctivitis. This is an allergic condition that causes itching in the eyes. It can also cause eye redness, watering, swelling, or irritation.

How it works

This drug belongs to a class of drugs called ophthalmic antihistamines. A class of drugs is a group of medications that work in a similar way.

More Details

How it works

This drug belongs to a class of drugs called ophthalmic antihistamines. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

This drug blocks the body’s release of a chemical called histamine. It also blocks histamine’s effect on the body. Histamine is released as part of the body’s immune response to fight disease. It increases inflammation (irritation and swelling), which can cause allergy symptoms. Blocking this chemical helps reduce eye symptoms caused by allergies. These include redness, itching, watering, swelling, or irritation.

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bepotastine Side Effects

Ophthalmic Solution

More Common Side Effects

The more common side effects that can occur with use of bepotastine include:

  • a mild bitter or metallic taste in your mouth after putting the drops in your eye(s)

  • headache

  • eye irritation

  • swelling of your nose and throat

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious Side Effects

Call your doctor right away if you have serious side effects. Call 9-1-1 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • Allergic reactions. Symptoms can include:

    • trouble breathing
    • swelling of your face, lips, throat, or tongue
    • itching or rash on your body
    • hives (itchy welts)
Pharmacist's Advice
Healthline Pharmacist Editorial Team

This drug doesn’t cause drowsiness.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
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bepotastine May Interact with Other Medications

Ophthalmic Solution

An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help prevent interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. 

To find out how bepotastine might interact with something else you’re taking, talk to your doctor or pharmacist.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

Pregnant women

This drug is a category C pregnancy drug. That means two things:

  1. Research in animals has shown adverse effects to the fetus when the mother takes the drug.
  2. There haven’t been enough studies done in humans to be certain how the drug might affect the fetus. 

Talk to your doctor if you’re pregnant or planning to become pregnant. This drug should only be used if the potential benefit justifies the potential risk to the fetus.

Women who are breast-feeding

It is not known if this drug may pass into breast milk or cause side effects in a child who is breast-fed. 

Talk to your doctor if you breast-feed your child. You may need to decide whether to stop breast-feeding or stop taking this medication.

For children

It hasn’t been established that this drug is safe and effective for use in children younger than 2 years of age. This drug should not be used in children younger than 2 years of age.

Allergies

This drug can cause a severe allergic reaction. Symptoms can include: 

  • trouble breathing
  • swelling of your face, lips, throat, or tongue
  • itching or rash on the body
  • hives (itchy welts) 

If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 9-1-1 or go to the nearest emergency room. 

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

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How to Take bepotastine (Dosage)

Ophthalmic Solution

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on: 

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

What are you taking this medication for?

Allergic conjunctivitis

Brand: Bepreve

Form: Ophthalmic solution 1.5%
Adult dosage (ages 18 years and older)

Put 1 drop into the affected eye(s) 2 times per day.

Child dosage (ages 2–17 years)

Put 1 drop into the affected eye(s) 2 times per day.

Child dosage (ages 0–1 years)

This medication has not been studied in very young children. It should not be used in children younger than 2 years of age.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.
Pharmacist's Advice
Healthline Pharmacist Editorial Team

This drug comes with risks if you don’t take it as prescribed.

If you stop taking the drug suddenly or don’t take it at all

Your allergy symptoms (eye itching, redness, watering, swelling, or irritation) may not improve. They may even get worse. 

If you miss doses or don’t take the drug on schedule

Your medication may not work as well or may stop working completely.

If you take too much

If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 9-1-1 or go to the nearest emergency room right away.

What to do if you miss a dose

Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.

How to tell if the drug is working

The allergy symptoms in your eyes should decrease or go away.

This drug is used for short-term treatment.

Important considerations for taking this drug

Store this drug carefully

  • Store this drug at a temperature between 55°F and 77°F (15°C and 25°C).
  • Don’t store this medication in moist or damp areas, such as bathrooms.

A prescription for this medication is refillable

You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

  • Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
  • Don’t worry about airport x-ray machines. They can’t hurt your medication.
  • You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled box with you.
  • Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Self-management

Your pharmacist can show you how to correctly put in the eye drops. Here are a few tips:

  • Wash your hands before using the medication. 
  • To prevent getting germs in your eyes, don’t touch your eyelids or other areas around your eyes with the tip of the dropper.
  • Keep the bottle tightly closed when you’re finished using the eye drops.
  • Don’t use this medication if the solution has changed color.
  • If you wear contact lenses, be sure to remove your contacts before putting the drops into your eyes. Then wait at least 10 minutes before putting your contact lenses back in.

Insurance

Many insurance companies require a prior authorization for this drug. This means your doctor may need to get approval from your insurance company before your insurance company will pay for the prescription.

Are there any alternatives?

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

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How Much Does bepotastine Cost?

Ophthalmic Solution

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These prices represent the lowest priced national pharmacies for bepotastine on GoodRx. They may be lower than your insurance.

Show Sources

Content developed in collaboration with University of Illinois-Chicago, Drug Information Group

Medically reviewed by Creighton University, Center for Drug Information and Evidence-Based Practice on November 17, 2015

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
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