Amcinonide | Side Effects, Dosage, Uses & More

Generic Name:

amcinonide, Topical cream

All Brands

  • Cyclocort (Discontinued)
A discontinued drug is a drug that has been taken off the market due to safety issues, shortage of raw materials, or low market demand.
SECTION 1 of 5

Highlights for amcinonide

Topical cream
1

Amcinonide is used to treat itching and inflammation caused by certain skin conditions. These include rashes, allergies, dermatitis, and eczema.

2

Amcinonide is available as a topical cream, lotion, and ointment you apply to your skin.

3

You should apply this drug as a thin layer to the affected area of your skin 2–3 times per day.

4

More common side effects of using this drug include itching, stinging, and burning.

5

In some cases, amcinonide can cause serious side effects. These include severe allergic reaction, growth delay in children, and adrenal problems.

IMPORTANT INFORMATION

Growth delay in children

Children may absorb higher amounts of amcinonide than adults. Your child’s growth and development may be delayed if they absorb significant amounts of this drug over a long period of time. Your child’s doctor should monitor their growth if they use amcinonide long–term.

Adrenal problems

In rare cases, using large amounts of this drug for a long time on a large area of skin may cause adrenal problems. This may cause high cortisol levels in your body. Symptoms include weight gain, fat deposits (around your stomach, upper back, face, and between your shoulders), stretch marks, thinning skin, slow healing wounds, acne, depression, anxiety, high blood pressure, high blood sugar levels, and bone loss. Covering the treated area with a dressing or a bandage also raises your risk.

Hair problems and acne

This drug may cause inflamed hair follicles (folliculitis), acne, and excessive hair growth over your body. Symptoms of inflamed hair follicles include redness, itching, and soreness around the follicle. These effects may be bothersome, but they can’t cause you serious harm.

Skin problems

This drug may cause skin problems. These can include:

  • burning, irritation, redness, or skin peeling that wasn’t there before you started using the drug
  • thinning of the upper layers of skin (skin atrophy)
  • stripes or lines on your skin (striae). These may look like reddish or purple-colored lines on your arms, face, legs, groin, or stomach.
  • infection. This drug may decrease your body’s ability to fight infections at the site where you apply it. Symptoms include redness or swelling that don’t improve or get worse.

Drug Features

Amcinonide a prescription drug. It’s available in these forms: topical cream, topical lotion, and topical ointment.

Amcinonide is only available as a generic drug.

This drug may be used as part of a combination therapy. That means you need to take it with other medications.

Why it's used

Amcinonide is used to treat itching, swelling, and redness caused by certain skin conditions. These include rashes, allergies, dermatitis, and eczema.

How it works

Amcinonide belongs to a class of drugs called topical corticosteroids. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

More Details

How it works

Amcinonide belongs to a class of drugs called topical corticosteroids. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

This drug decreases the body’s ability to make chemicals that cause inflammation (prostaglandins).These chemicals are normally released when your skin reacts to allergens or irritation. This widens your blood vessels and causes other inflammatory substances to be released. The area of skin becomes red, swollen, and itchy. This drug reduces swelling, redness, and itching by stopping these chemicals from being released in the skin.

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amcinonide Side Effects

Topical cream

More common side effects

The more common side effects of amcinonide can include:

  • burning

  • itching

  • skin irritation

  • stinging

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious side effects

Call your doctor right away if you have serious side effects. Call 9-1-1 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
  • Severe allergic reaction. Symptoms can include:
    • hives
    • itching
    • rash
    • swelling of your eyes, face, lips, throat, or tongue
    • trouble breathing
  • Growth delay in children
  • Adrenal problems. This is more likely with long-term use of amcinonide over a large area of your body. Covering the treated area with a dressing or a bandage also raises your risk Adrenal issues include:

    • high cortisol levels. Symptoms can include:
      • weight gain
      • fat deposits around your stomach, upper back, face, and between your shoulders
      • stretch marks
      • thinning skin
      • slow healing wounds
      • acne
      • depression
      • anxiety
      • high blood pressure
      • high blood sugar levels
      • bone loss
Pharmacist's Advice
Healthline Pharmacist Editorial Team
Amcinonide doesn’t cause drowsiness.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
SECTION 3 of 5

amcinonide May Interact with Other Medications

Topical cream

An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

People with an infection

This drug may lower your body's ability to fight infections. You shouldn’t apply amcinonide to areas of your skin that are infected.

People with sores or broken skin

You shouldn’t apply amcinonide to an open sore or broken skin. This may cause more of the drug to be absorbed into your bloodstream. This may result in side effects.

Pregnant women

Amcinonide is a category C pregnancy drug. That means two things:

  1. Research in animals has shown adverse effects to the fetus when the mother takes the drug.
  2. There haven’t been enough studies done in humans to be certain how the drug might affect the fetus.

Talk to your doctor if you’re pregnant or planning to become pregnant. This drug should be used only if the potential benefit justifies the potential risk to the fetus.

Women who are breast-feeding

Amcinonide may pass into breast milk and may cause side effects in a child who is breast-fed.

Talk to your doctor if you breast-feed your baby. You may need to decide whether to stop breast-feeding or stop taking this medication.

For children

Children may absorb higher amounts of amcinonide than adults. Your child’s growth and development may be delayed if they absorb significant amounts of this drug over a long period of time. Your child’s doctor should monitor their growth if they use amcinonide long–term.

When to call the doctor

Contact your healthcare provider if:

  • your skin problems don’t get better or become worse
  • the site where you apply amcinonide looks infected. Signs of infection include redness, warmth, swelling, and pain.

Allergies

Amcinonide can cause a severe allergic reaction. Symptoms can include:

  • swelling of your eyes, face, lips, throat, or tongue
  • hives
  • itching
  • trouble breathing
  • rash

Call 9-1-1 or go to the nearest emergency room if you develop these symptoms.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death). If you have an allergic reaction to amcinonide, you may react to other corticosteroids.

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How to Take amcinonide (Dosage)

Topical cream

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

What are you taking this medication for?

Relieve inflammation and itching of your skin

Amcinonide

Form: topical cream
Strengths: 0.1%
Form: topical lotion
Strengths: 0.1%
Form: topical ointment
Strengths: 0.1%
Adult dosage (ages 18 years and older):

Apply a thin layer to the affected area of your skin 2–3 times per day.

Child dosage (ages 0–17 years):

Apply a thin layer to the affected area of your skin 2–3 times per day.

Dosage Warnings

Children may absorb more amcinonide through their skin than adults. This may increase their chance of serious side effects. To reduce this risk, amcinonide should be used for the shortest amount of time possible to control itching and inflammation. If this drug needs to be used on an infant’s diaper area, they shouldn’t wear tight-fitting diapers or plastic pants.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.
Pharmacist's Advice
Healthline Pharmacist Editorial Team

Amcinonide comes with risks if you don’t take it as prescribed.

If you stop taking the drug or don’t take it at all

Your redness, itching, and swelling may not improve or may get worse.

If you take too much

You could have dangerous levels of the drug in your body. This can cause adrenal problems and high cortisol levels. Symptoms can include:

  • weight gain
  • fat deposits around your stomach, upper back, face, and between your shoulders
  • stretch marks
  • thinning skin
  • slow healing wounds
  • acne
  • depression
  • anxiety
  • high blood pressure
  • high blood sugar levels
  • bone loss

If you swallowed or think you’ve used too much of the drug, act right away. Call your doctor or local poison control center, or go to the nearest emergency room.

What to do if you miss a dose

Apply amcinonide topically to the affected area as soon as you remember. But if you remember just a few hours before your next scheduled dose, skip the missed dose and go back to your regular dosing schedule.

How to tell if the drug is working

Your redness, itching, and swelling will improve.

Amcinonide may be used for short-term or long-term treatment depending on your medical condition.

Important considerations for taking amcinonide
You can take amcinonide with or without food. You can take amcinonide with or without food.
Storage Store this drug carefully See Details
Refillable Prescription is refillable See Details
Travel  Travel See Details
Self Management Self-management See Details
Clinical Monitoring Clinical monitoring See Details
Not Usually Stocked Not every pharmacy stocks this drug. When filling your prescription, be sure to call ahead.
Prior Authorization Needed Insurance See Details

Store this drug carefully

  • Store amcinonide at room temperature. Keep it from 68°F to 77°F (20°C to 25°C).
  • Don’t freeze this drug.
  • Keep it away from high temperatures.
  • Don’t store this medication in moist or damp areas, such as bathrooms.

Prescription is refillable

You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

  • Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
  • Don’t worry about airport x-ray machines. They can’t hurt your medication.
  • You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled box with you.
  • Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Self-management

  • Only apply amcinonide to your skin. Don’t take this drug by mouth. Avoid getting amcinonide into your mouth, nose, and eyes.
  • Wash your hands before and after using this drug. However, if you’re using it on your hands, don’t wash your hands after applying it.
  • Clean and dry the affected area before applying amcinonide.
  • Don’t apply this drug to your face, underarms, or groin area unless your doctor tells you to.
  • Don’t cover the treated area with bandages or dressings unless your doctor tells you to. Covering the area can increase the amount of medicine your skin absorbs. This may lead to more side effects.

Clinical monitoring

You and your doctor should monitor certain health issues. This can help make sure you stay safe while you take this drug. These issues include:

  • Growth in children. In rare cases, using amcinonide for a long time may slow a child’s growth. Your doctor may need to check your child’s height and monitor their growth.
  • Adrenal gland function. Your doctor may do tests (free-cortisol test, ACTH stimulation test) to check for side effects of this drug. You may have these tests done if you apply amcinonide over a large area for a long period of time.

Insurance

Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription.

Are there any alternatives?

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

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How Much Does amcinonide Cost?

Topical cream

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Lowest price for amcinonide

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These prices represent the lowest priced national pharmacies for amcinonide on GoodRx. They may be lower than your insurance.

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Content developed in collaboration with University of Illinois-Chicago, Drug Information Group

Medically reviewed by Creighton University, Center for Drug Information and Evidence-Based Practice on September 29, 2015

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
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