Aclidinium | Side Effects, Dosage, Uses & More
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Generic Name:

aclidinium, Inhalation powder

Generic Name:

All Brands

  • TUDORZA PRESSAIR
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Highlights for aclidinium

Inhalation powder
1

Aclidinium is used to treat symptoms of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.

2

This drug comes in the form of a dry powder inhaler.

3

Aclidinium is available as a brand-name drug called Tudorza Pressair. It isn’t available as a generic drug.

4

The more common side effects of this drug include headache, cough, and upper respiratory tract infection (runny or stuffy nose, body aches, sore throat, tiredness).

5

In some cases, aclidinium can cause serious side effects. These include eye damage, pain when urinating, and trouble passing urine.

IMPORTANT INFORMATION

Worsening breathing problems

Rarely, inhaled medicines like this drug can worsen shortness of breath or other breathing problems. Call your doctor and stop using this drug right away if this happens to you.

Not a rescue medication

This drug isn’t a rescue drug. It shouldn’t be used to treat sudden breathing problems. Your doctor may give you another drug to use for sudden breathing problems.

Drug features

This drug is a prescription drug. It’s available as a dry powder inhaler.

This drug isn’t available as a generic drug. It’s only available as the brand-name drug Tudorza Pressair.

This drug may be used as part of a combination therapy. This means you may need to take it with other medications.

Why it’s used

This drug is used to treat symptoms of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. This drug isn’t a rescue medicine and shouldn’t be used to treat sudden breathing problems.

How it works

This drug belongs to a class of drugs called inhaled anticholinergic medications. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

More Details

How it works

This drug belongs to a class of drugs called inhaled anticholinergic medications. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

This drug relaxes the muscles of your lungs. This decreases and prevents shortness of breath, which helps you breathe better.

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aclidinium Side Effects

Inhalation powder

More Common Side Effects

Some of the more common side effects that can occur with use of aclidinium include:

  • headache

  • cough

  • upper respiratory tract infection. Symptoms include:

    • runny or stuffy nose
    • body aches
    • sore throat
    • tiredness

Serious Side Effects

Call your doctor right away if you have serious side effects. Call 9-1-1 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
  • Worsening breathing problems. Inhaled medicines, like aclidinium, can rarely cause worsening of shortness of breath or other breathing problems.
Pharmacist's Advice
Healthline Pharmacist Editorial Team

This drug doesn’t cause drowsiness.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
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aclidinium May Interact with Other Medications

Inhalation powder

Aclidinium can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Medications that might interact with this drug

Breathing problems drugs

Taking aclidinium with other drugs used to treat breathing problems may increase your risk of side effects. You shouldn’t use these drugs together.

These drugs include:

  • anticholinergic drugs, such as:
    • ipratropium
    • tiotropium

Heart problems drugs

Atropine is used to treat heart problems. Taking aclidinium with atropine may increase your risk of side effects. You shouldn’t use these drugs together.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

People with narrow-angle glaucoma

If you have glaucoma, using this drug can worsen your condition. Tell your doctor right away if you have new or worsening eye pain or discomfort, blurred vision, or see bright circles around lights or objects (halos) while you’re taking this drug.

People with trouble urinating (urinary retention)

If you have urinary retention, using this drug can worsen your condition. Tell your doctor right away if you have trouble passing urine or painful urination while you’re taking this drug.

Pregnant women

This drug is a category C pregnancy drug. That means two things:

  1. Research in animals has shown adverse effects to the fetus when the mother takes the drug.
  2. There haven’t been enough studies done in humans to be certain how the drug might affect the fetus.

Talk to your doctor if you’re pregnant or planning to become pregnant. This drug should be used only if the potential benefit justifies the potential risk to the fetus.

Women who are breast-feeding

This drug may pass into breast milk and may cause side effects in a child who is breast-fed.

Talk to your doctor if you breast-feed your baby. You may need to decide whether to stop breast-feeding or stop taking this medication.

For children

The safety and effectiveness of this drug haven’t been established in children younger than 18 years. Chronic obstructive pulmonary disease (COPD) doesn’t normally occur in children.

When to call the doctor

Call your doctor if you need to use your rescue inhaler more often than usual. This may be a sign that this drug isn’t working, and that your breathing problem is getting worse.

Allergies

This drug can cause a severe allergic reaction. Symptoms can include:

  • itching
  • swelling of the lips, tongue, or throat
  • skin rash
  • trouble breathing
  • hives

Call 9-1-1 or go to the nearest emergency room if you develop these symptoms.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death). Use extreme caution if you’ve had an allergic reaction to atropine or milk proteins (the powder for inhalation contains lactose).

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How to Take aclidinium (Dosage)

Inhalation powder

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

What are you taking this medication for?

Chronic obstructive pulmonary disease (COPD)

Brand:Tudorza Pressair

Form: Dry powder inhaler
Strengths: 400 mcg
Adult dosage (ages 18 years and older):

The dose is one inhalation or puff taken by mouth twice per day. Each inhalation or puff provides a dose of 400 mcg.

Child dosage (ages 0–17 years):

This medication hasn’t been studied in children. It shouldn’t be used in people younger than 18 years.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.
Pharmacist's Advice
Healthline Pharmacist Editorial Team

This drug comes with risks if you don’t take it as prescribed.

If you stop taking the drug or don’t take it at all

You may have worsened shortness of breath or other breathing problems.

If you miss doses or don’t take the drug on schedule

Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

If you take too much

You could have dangerous levels of the drug in your body. Taking too much may cause you to have more side effects from this drug, such as eye and urine problems.

If you think you’ve taken too much of the drug, act right away. Call your doctor or local poison control center, or go to the nearest emergency room.

What to do if you miss a dose

Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.

How to tell if the drug is working

You may be able to tell that this drug is working if you have less shortness of breath or other breathing problems.

This drug is used for long-term treatment.

Important considerations for taking this drug

You can take this drug with or without food

You shouldn’t have any food or drink in your mouth when you inhale this drug.

Store this drug at room temperature

Keep it at 77°F (25°C). It can be kept for a short time between 59°F to 86°F (15°C to 30°C). Keep it away from high temperatures.

Store this drug inside the sealed pouch it comes in. Wait to open it until right before using it. Throw the inhaler away after 45 days or when you’ve used all the doses, whichever comes first.

Don’t store this medication in moist or damp areas, such as bathrooms.

Prescription is refillable

You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

  • Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
  • Don’t worry about airport x-ray machines. They can’t hurt your medication.
  • You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled box with you.
  • Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Self-management

Your doctor or nurse will show you how to use your inhaler.

To use the inhaler, follow these steps:

  • Step 1: Remove the protective cap by lightly squeezing the arrows marked on each side of the cap and pulling outwards. Make sure that nothing is blocking the mouthpiece.
  • Step 2: Hold the inhaler with the mouthpiece facing you, but don’t put it inside your mouth. The green button should be facing straight up.
  • Step 3: Before you put the inhaler into your mouth, press the green button all the way down. Then release the green button. Don’t continue to hold the green button down.
  • Step 4: Stop and check the control window to make sure your dose is ready for inhalation. Look to see if the colored control window has changed from red to green.
    • The green control window tells you that your medicine is ready.
    • If the control window stays red, repeat the “press and release” actions in Step 3 until the control window is green.
    • Now the dose is ready to be inhaled.
  • Step 5: Before you put the inhaler into your mouth, breathe out completely. Don’t breathe out into the inhaler.
    • Put your lips tightly around the mouthpiece of the inhaler. Breathe in quickly and deeply through your mouth. This quick, deep breath makes sure that you get enough of the medication from the inhaler into your lungs.
    • Breathe in until you hear a “click” sound. Keep breathing in, even after you’ve heard the inhaler “click” to be sure you get the full dose.
  • Step 6: Remove the inhaler from your mouth and hold your breath for as long as it’s comfortable. Then breathe out slowly through your nose.
    • Some people may taste the medicine during their inhalation. Don’t take an extra dose even if you don’t taste anything after inhaling.
  • Step 7: Stop and check the control window. Make sure you’ve used your inhaler correctly.
    • Check if the control window has turned from green to red. If the window is red, you’ve inhaled your full dose of medicine correctly.
    • If the colored control window is still green, repeat Steps 5 and 6.
    • If the window still doesn’t change to red, you may have forgotten to release the green button before inhaling or you may not have inhaled correctly. If that happens, repeat Steps 5 and 6 again.
    • Make sure you have released the green button and take a quick and deep breath in through the mouthpiece.
    • If you’re unable to inhale correctly after several attempts, call your doctor.
  • Step 8: Once the window has turned red, place the protective cap back onto the inhaler by pressing it back onto the mouthpiece.

Clinical monitoring

You and your doctor should monitor certain health issues. This can help make sure you stay safe while you take this drug. These issues include:

  • Breathing. Your doctor will ask you about your shortness of breath, your ability to exercise and other activities of your daily life.

Insurance

Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription.

Are there any alternatives?

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

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How Much Does aclidinium Cost?

Inhalation powder

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These prices represent the lowest priced national pharmacies for aclidinium on GoodRx. They may be lower than your insurance.

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Content developed in collaboration with University of Illinois-Chicago, Drug Information Group

Medically reviewed by Creighton University, Center for Drug Information and Evidence-Based Practice on October 9, 2015

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
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