Drug Interaction Checker

Food significantly reduces the effectiveness of Sodium Oxybate. You should take your doses on an empty stomach. This means you should try to eat well before (i.e., several hours prior) going to sleep and taking the first bedtime dose. You should eat your evening meal and take your doses at roughly the same times daily to minimize any effects of food on your response to Sodium Oxybate treatment.

Limit caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking Stimulant medicines. Stimulants include drugs used for weight loss, narcolepsy, and Attention-Deficit-Hyperactivity Disorder (ADHD). Examples include: Amphetamine, Adderall, Concerta, Cylert, Dextroamphetamine, Dexedrine, Metadate, Provigil, Ritalin, or Xyrem. Also avoid medicines containing additional Caffeine whenever possible. Side effects from Psychostimulants may get worse if you take excessive Caffeine. Taking a high amount of Caffeine can increase the risk of nausea, nervousness, palpitations, problems with sleep, rapid heartbeat, or other side effects.