Drug Interaction Checker

Alcohol may cause drowsiness and other side effects and thus may decrease the effectiveness of Modafinil. You should avoid alcoholic beverages while taking this drug.

You can take Modafinil with or without most foods. However, Grapefruit-juice and grapefruit may increase the actions or side effects of Modafinil. Do not significantly alter your intake of grapefruit juice while on Modafinil, as increasing grapefruit intake may lead to irritability or nervousness.

Limit caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking Stimulant medicines. Stimulants include drugs used for weight loss, narcolepsy, and Attention-Deficit-Hyperactivity Disorder (ADHD). Examples include: Amphetamine, Adderall, Concerta, Cylert, Dextroamphetamine, Dexedrine, Metadate, Provigil, Ritalin, or Xyrem. Also avoid medicines containing additional Caffeine whenever possible. Side effects from Psychostimulants may get worse if you take excessive Caffeine. Taking a high amount of Caffeine can increase the risk of nausea, nervousness, palpitations, problems with sleep, rapid heartbeat, or other side effects.