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Drug Interaction Checker

All     Severe     Moderate     Minor
3 Drug Interactions Found
Severe severe interaction
ergonovine+Grapefruit juice
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Taking grapefruit juice with Ergot Alkaloids might increase the risk of nausea, nervousness, chest pain, high blood pressure, palpitations, or other serious side effects, like pain, numbness or reduced circulation to the hands, feet or legs. Ergot Alkaloids include, but are not limited to, Cafergot, Ergotrate, Ergostat, Hydergine, Methergine, Migranal, Sansert or Wigraine. It is best to avoid grapefruit juice while taking Ergot Alkaloids to reduce the chance of Ergot Alkaloid-related side effects.
Severe severe interaction
ergonovine+Tobacco
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It is recommended to avoid nicotine (examples: Nicotine patches or gum) and tobacco while taking any Ergot-type medications. Side effects from Ergot Alkaloids may get worse if you take Nicotine or if you smoke tobacco. Ergot Alkaloids include, but are not limited to, Cafergot, Ergotrate, Ergostat, Hydergine, Methergine, Migranal, Sansert or Wigraine. Side effects might include anxiety, chest pain, numbness in the fingers or toes, tingling, or vision changes.
Moderate moderate interaction
mifepristone+Grapefruit juice
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Mifepristone (also known as RU-486 or Mifeprex) does not interact with most foods. Grapefruit juice and grapefruit-containing foods may increase the effects of Mifepristone, RU-486, which may worsen side effects like abdominal pain, diarrhea, headache, or uterine cramps. Do not significantly alter your grapefruit juice intake while taking this drug.
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This feature is for informational purposes only and should not be used to replace the care and information received from your healthcare provider. Please consult a healthcare professional with any health concerns you may have.

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